Publications

  • Hsieh J. 2012 May 15. Orchestrating transcriptional control of adult neurogenesis. Genes Dev. 26(10):1010-21.
  • Gao Z, Ding P, Hsieh J. Profiling of REST-Dependent microRNAs Reveals Dynamic Modes of Expression. Front Neurosci. 2012;6:67. [Epub 2012 May 10].
  • Petrik D, Jiang Y, Birnbaum SG, Powell CM, Kim MS, Hsieh J, Eisch AJ. FASEB J. 2012 Aug. Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule. [Epub 2012 Apr 27.]
  • Zhengliang Gao, Kerstin Ure, Mostafa Nashaat, Laura Yuan, Robert Hammer, and Jenny Hsieh. 2011. The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. Journal of Neuroscience 31(26): 9772-86.
  • Ling Zhang, Peng Li, Tiffany Hsu, Jay Schneider, Robert Bachoo, and Jenny Hsieh. 2011. Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression. Differentiation 81(4): 233-42.
  • Yanhong Shi, Xinyu Zhao, Jenny Hsieh, Hynek Wichterle, Soren Impey, Sourav Banerjee, Pierre Neveu, and Kenneth S. Kosik. MicroRNA regulation of neural stem cells and neurogenesis. 2010. Journal of Neuroscience 30: 14931-14936.
  • JL Ables, NA Decarolis, MA Johnson, PD Rivera, Z Gao, DC Cooper, F Radtke, J Hsieh, and AJ Eisch. 2010. Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. Journal of Neuroscience 30(31): 10484-92.
  • AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, P Huntington, SE Goldman, CH Shen, M Capota, JK Britt, T Kotti, K Ure, DJ Brat, NS Williams, KS MacMillan, J Naidoo, L Melito, J Hsieh, J De Brabander, JM Ready, and SL McKnight. 2010. Discovery of a proneurogenic, neuroprotective chemical. Cell 142(1): 39-51.
  • Jenny Hsieh and Amelia J Eisch. Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. 2010. Neurobiology of Disease Epub Jan 28.
  • Ying Chen, Heng Wu, Hisami Koito, Jianrong Li, Jenny Hoang, Shuzong Wang, Sabine S. Escobar, Alex Gow, Heather A. Arnett, Bruce D. Trapp, Nitin J. Karandikar, Jenny Hsieh and Q. Richard Lu. The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell-intrinsic timer of myelination. 2009. Nature Neuroscience 12:1398-406.
  • Tomoko Kuwabara, Jenny Hsieh, Alysson Muotri, Gene Yeo, Masaki Warashina, D. Chichung Lie, Lynne Moore, Kinichi Nakashima, Makoto Asashima, Fred H. Gage. Wnt-mediated activation of NeuroD1 and retroelements during adult neurogenesis. 2009. Nature Neuroscience 12: 1097-1105.
  • Zhengliang Gao, Kerstin Ure, Jessica Ables, Diane Lagace, Sandra Goebbels, Klause-Armin Nave, Amelia Eisch, and Jenny Hsieh. Neurod1 is essential for the survival and maturation of adult-born neurons. 2009. Nature Neuroscience 12: 1090-1092.
  • Feng Ye, Ying Chen, Thao Nguyen Hoang, Rusty Montgomery, Hong Bu, Xiang-hui Zhao, Tom Hu, Johan van Es, Hans Clevers, Makoto Taketo, Jenny Hsieh, Rhonda Bassel-Duby, Eric N. Olson, and Q. Richard Lu. HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction. 2009. Nature Neuroscience 12: 829-38.
  • Rusty Montgomery, Jenny Hsieh, Ana Barbosa, James Richardson, and Eric N. Olson. Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. 2009. Proc Natl Acad Sci USA 106: 7876-81.
  • Jun Kohyama, Takuro Kojima, Eriko Takatsuka, Toru Yamashita, Jun Namiki, Jenny Hsieh, Fred H. Gage, Masakazu Namihira, Hideyuki Okano, Kazunobu Sawamoto, and Kinichi Nakashima. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. 2008. Proc Natl Acad Sci USA 105: 18012-18017.
  • Jay W. Schneider, Zhengliang Gao, Shijie Li, Midhat Farooqi, Tie-Shan Tang, Ilya Bezprozvanny, Douglas E. Frantz, and Jenny Hsieh. Small-molecule activation of neuronal cell fate. 2008. Nature Chemical Biology 4: 408-10.
  • Hesham Sadek, Britta Hannack, Elizabeth Choe, Jessica Wang, Shuaib Latif, Mary G. Garry, Daniel J. Garry, Jamie Longgood, Douglas E. Frantz, Eric N. Olson, Jenny Hsieh, and Jay W. Schneider. Cardiogenic small molecules that enhance stem cell function in myocardial repair. 2008. Proc Natl Acad Sci USA 105: 6063-8.
  • Sebastian Jessberger, Kinichi Nakashima, Gregory Clemenson, Eunice Mejia, Emily Mathews, Kerstin Ure, Shiori Ogawa, Christopher M. Sinton, Fred H. Gage, and Jenny Hsieh. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. 2007. Journal of Neuroscience, 27: 5967-75.
  • Jenny Hsieh and Fred H. Gage. 2005. Chromatin remodeling in neural development and plasticity. Current Opinion in Cell Biology, 17: 664-71.
  • Liou Y. Sun, M. Steven Evans, Jenny Hsieh, Jacob Panici, and Andrzej Bartke. 2004. Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice. Endocrinology.
  • Jenny Hsieh, Kinichi Nakashima, Tomoko Kuwabara, Eunice Mejia, and Fred H. Gage. 2004. HDAC inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci USA 101(47): 16659-64.
  • Jenny Hsieh and Fred H. Gage. 2004. Epigenetic control of neural stem cell fate. Current Opinion in Genetics & Development, 14: 461-469.
  • Tomoko Kuwabara, Jenny Hsieh, Kinichi Nakashima, Kazunari Taira, and Fred H. Gage. 2004. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell, 116: 779-793.
  • Jenny Hsieh, James B. Aimone, Brian K. Kaspar, Tomoko Kuwabara, Kinichi Nakashima, and Fred H. Gage. 2004. IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. Journal of Cell Biology, 164: 111-122.
  • Jenny Hsieh and Andrew Fire. 2000. Recognition and silencing of repeated DNA. Annual Review of Genetics, 34: 187-204.
  • Jenny Hsieh, Jing Liu, Steve Kostas, Chieh Chang, Paul Sternberg, and Andrew Fire. 1999. The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans. Genes and Development, Nov 15; 13(22): 2958-70.