Publications


  1. Robertson, S.M. and Lin, R. "The oocyte-to-embryo transition." Invited chapter for Germline Development in C. elegans (Adv. Exp. Med. Biol., T. Schedl, ed.) 2012. (in press)

  2. Robertson, S.M. and Lin, R. Invited auto-commentary ("Extra Views") regarding our article Yang et al, 2011 for the inaugural issue of Worm (Landes Bioscience, publisher), Jan 2012. (in press)

  3. Oldenbroek, M., Robertson, S.M., Guven-Ozkan, T., Gore, S., Nishi, Y., and Lin, R. (2012) Multiple RNA-binding proteins function combinatorially to control the soma-restricted expression pattern of the E3 ligase subunit ZIF-1. Dev. Biol. (in press)

  4. Yang, X-D., Huang, S., Lo, M-C., Mizumoto, K., Sawa, H., Xu, W., Robertson, S., and Lin, R. (2011) Distinct and mutually inhibitory binding by two divergent β-catenins coordinates TCF levels and activity in C. elegans. Development 138:4255-4265.

  5. Robertson, S. M., Lo, M-C., Odom, R., Yang, X-D., Medina, J., Huang, S., and Lin, R. (2011). Functional analyses of vertebrate TCF proteins in C. elegans embryos. Dev. Biol. 355:115-123.

  6. Guven-Ozkan*, T., Robertson*, S. M., Nishi, Y., and Lin, R. (2010). zif-1 translational repression defines a second, mutually exclusive OMA function in germline transcriptional repression. Development 137:3373-3382. * equal contribution.

  7. Guven-Ozkan, T., Y. Nishi, S. M. Robertson, R. Lin. 2008. Global transcriptional repression in C. elegans germline precursors by regulated sequestration of TAF-4. CELL 135:149-160.

  8. Guo, Y.-M., S. Chen, P. Shetty, R. Lin, W.-H. Li. 2008. Imaging dynamic cell-cell junvtional coupling in vivo using Trojan-LAMP. Nature Meth. 5:835-841.

  9. Nishi, Y., E. Rogers, S. M. Robertson, R. Lin. 2008. Polo kinases regulate C. elegans embryonic polarity via binding to DYRK2-primed MEX-5 and MEX-6. Development 135: 687-697.

  10. Alcazar, R.M., R. Lin, A.Z. Fire. 2008. Transmission dynamics of heritable silencing induced by double-stranded RNA in Caenorhabditis elegans. Genetics 180: 1275-1288.

  11. Huang, S., P. Shetty, S. M. Robertson, R. Lin. 2007. Binary cell fate specification during C. elegans embryogenesis driven by reiterated reciprocal asymmetry of TCF/POP-1 and its coactivator b-catenin/SYS-1. Development 134: 2685-2695.

  12. Nishi, Y. and R. Lin. 2005. DYRK2 and GSK-3 phosphorylate and promote the timely degradation of OMA-1, a key regulator of the oocyte-to-embryo transition in C. elegans. Dev. Biol. 288:139-149.

  13. Shetty, P., M-C Lo, S. M. Robertson, and R. Lin. 2005. C. elegans TCF protein, POP-1, converts from repressor to activator as a result of Wnt-induced lowering of nuclear levels. Dev. Biol. 285:584-592.

  14. Robertson, S. M., P. Shetty, R. Lin. 2004. Identification of lineage-specific zygotic transcripts in early C. elegans embryos. Dev Biol. 276:493-507.

  15. Lo, M-C., F. Gay, R. Odom, Y. Shi, R. Lin. 2004. A 14-3-3 protein, PAR-5, mediates nuclear export of POP-1 in Wnt/MAP kinase responsive cells in C. elegans embryos. CELL 117:95-106.

  16. Lin, R. Regulation of the degradation of maternal proteins in early embryos by OMA-1, a C. elegans protein functioning in oocyte maturation. 2003. Dev. Biol. 258:226-239.

  17. Gay, F. D. Calvo, M.-C. Lo, J. Ceron, M. F. Maduro, R. Lin, and Y. Shi 2003. Acetylation regulates subcellular localization of the Wnt signaling nuclear effector POP-1. Gene & Dev. 17:717-722.

  18. Maduro, M. F. R. Lin, and J. H. Rothman. 2002. Dynamics of a developmental switch: recursive intracellular and intranuclear redistribution of Caenorhabditis elegans POP-1 parallels Wnt-inhibited transcriptional repression. Dev. Biol. 248: 128-142.

  19. Rogers, E., J. D. Bishop, J. A. Waddle, J. Schumacher, and R. Lin. 2002. The Aurora Kinase AIR-2 Functions in the Release of Chromosome Cohesion in C. elegans Meiosis. J. Cell Biol. 157: 219-229.

  20. Reuben, M. and R. Lin. 2002. Germline X Chromosomes Exhibit Contrasting Patterns of Histone H3 Methylation in C. elegans. Dev. Biol. 245: 71-82.

  21. Detwiler, M. R., M. Reuben, X. Li, E. Rogers, and R. Lin. 2001. Two zinc finger proteins, OMA-1 and OMA-2, are redundantly required for oocyte maturation in C. elegans. Dev. Cell 1: 187-199.

  22. Hsu, J-Y., Z-W. Sun, X. Li, M. Reuben, K. Tatchell, D. K. Bishop, J. M. Grushcow, R. Lin, M. M. Smith, and C. D. Allis. 2000. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. CELL 102:279-291.

  23. Schubert, C. M., R. Lin, C. J. de Vries, R. H. A. Plasterk and J. R. Priess. 2000. MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos. Mol Cell 5:671-682.

  24. R. Lin and L. Avery. 1999. RNA Interference: Policing Rogue genes. Nature. 402: 128-129.

  25. Shin, T. H., J. Yasuda, C. E. Rocheleau, R. Lin, M. Soto1, R. J. Davis, and C. C. Mello. 1999. MOM-4, a MAP kinase kinase kinase related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans. Mol Cell. 4: 275-280.

  26. Rocheleau, C. E., J. Yasuda, T. H. Shin, R. Lin, H. Sawa, H. Okano, J. R. Priess, R. J. Davis, and C. C. Mello. 1999. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. CELL. 97: 717-726.

  27. Lin, R., R. Hill, and J. R. Priess. 1998. POP-1 and anterior-posterior fate decisions in C. elegans embryos. CELL. 92: 229-239.

  28. Rocheleau, C., W. D. Downs, R. Lin, C. Wittmann, Y. Bei, Y-H Cha, M. Ali, J. R. Priess, C. C. Mello. 1997. Wnt signaling and an APC related gene specify endoderm in early C. elegans embryos. CELL. 90: 707-717.

  29. Lin, R., C. D. Allis and S. J. Elledge. 1996. PAT1, an evolutionarily conserved acetyltransferase homolog, is required for multiple steps in the cell cycle. Genes to Cells 1: 923-942.

  30. Lin, R., S. Thompson and J. R. Priess. 1995. pop-1 encodes an HMG-box protein required for the specification of a mesoderm precursor in early C. elegans embryos. CELL. 83: 599-610.

  31. Meistrich, M. L., P. K. Trostle-Weige, R. Lin, Y. M. Bhatnagar, and C. D. Allis. 1992. Highly acetylated H4 is associated with histone displacement in rat spermatids. Mol Reprod Dev. 31: 170-181.

  32. Lin, R., R. G. Cook, and C. D. Allis. 1991. Proteolytic removal of core histone amino-termini and dephosphorylation of histone H1 correlate with the formation of condensed chromatin and transcriptional silencing during Tetrahymena development. G&D 5: 1601-1610.

  33. Davie, J. R., R. Lin, and C. D. Allis. 1991. Timing of the appearance of ubiquitinated histones in the developing new macronuclei of Tetrahymena thermophila. Biochem Cell Biol. 69: 66-71.

  34. Olins, D. E., A. L. Olins, A. Herrmann, R. Lin, C. D. Allis, and M. Robert-Nicoud. 1991. Localization of acetylated histone H4 in the macronucleus of Euplotes. Chromosoma 100: 377-385.

  35. Lin, R., J. W. Leone, R. G. Cook and C. D. Allis. 1989. Antibodies specific to acetylated histones document the existence of deposition- and transcription-related histone acetylation in Tetrahymena. J. Cell. Biol. 108: 1577-1588.