Publications

Journal Articles

1. Lu, H., Golay, X., and van Zijl, P.C. Intervoxel Heterogeneity of Event-Related Functional Magnetic Resonance Imaging Responses as a Function of T1 Weighting. NeuroImage 17: 943-955, 2002.

2. Lu, H., Golay, X., Pekar, J.J., and van Zijl, P.C. Functional Magnetic Resonance Imaging Based on Changes in Vascular Space Occupancy. Magnetic Resonance in Medicine 50: 263-274, 2003.

3. Hendrikse, J., Lu, H., van der Grond, J., van Zijl, P.C., and Golay, X. Fast Measurements of Cerebral Perfusion and Arterial Hemodynamics during Visual Stimulation with TURBO-TILT fMRI. Magnetic Resonance in Medicine 50: 429-433, 2003.

4. Lu, H., van Zijl, P.C., Hendrikse, J., Golay, X. Multiple Acquisition with Global Inversion Cycling (MAGIC): a Multi-slice Technique for Vascular-Space-Occupancy Dependent fMRI. Magnetic Resonance in Medicine 51: 9-15, 2004.

5. Hendrikse, J., van der Grond, J., Lu, H., van Zijl, P.C., and Golay, X. Flow territory mapping of the cerebral arteries with regional perfusion MRI (RPI). Stroke 35: 882-887, 2004.

6. Lu, H., Golay, X., Pekar, J.J., and van Zijl, P.C. Sustained post-stimulus elevation in cerebral oxygen utilization following vascular recovery. Journal of Cerebral Blood Flow and Metabolism 24: 764-770, 2004.

7. Lu, H., Clingman, C., Golay, X., and van Zijl, P.C. Determination of Longitudinal Relaxation Time (T1) of Blood at 3.0 Tesla. Magnetic Resonance in Medicine 52: 679-682, 2004.

8. Lu, H., and van Zijl, P.C. Experimental Separation of Intra and Extravascular BOLD Effects using Multi-echo VASO and BOLD fMRI at 1.5T and 3.0T. Magnetic Resonance in Medicine 53: 808-816, 2005.

9. Jensen, J.H., Helpern, J.A., Ramani, A., Lu, H., and Kaczynski, K. Diffusional Kurtosis Imaging: The Quantification of Non-Gaussian Water Diffusion by Means of MRI. Magnetic Resonance in Medicine 53: 1432-1440, 2005.

10. Lu, H., Nagae-Poetscher, L.M., Golay, X., Lin D., Pomper M.G., and van Zijl, P.C. Routine Clinical Brain MRI Sequences for Use at 3.0 Tesla. Journal of Magnetic Resonance Imaging 22: 13-22, 2005.

11. Lu, H., Basso, G., Serences, J.T., Yantis, S., Golay, X., and van Zijl, P.C. Retinotopic mapping in human visual cortex using Vascular-Space-Occupancy (VASO) dependent fMRI. NeuroReport 16: 1635-1640, 2005.

12. Lu, H., Law, M., Johnson, G., Ge, Y., van Zijl, P.C., and Helpern, J.A. A Novel Approach to Measure Absolute Cerebral Blood Volume using Vascular-Space-Occupancy (VASO) Dependent MRI. Magnetic Resonance in Medicine 54: 1403-1411, 2005.

13. van Laar P.J., Hendrikse, J., Golay X., Lu, H., van Osch, M.J. and van der Grond, J. In vivo Flow Territory Mapping of Majoy Brain Feeding Arteries. NeuroImage 29: 136-144. 2006.

14. Gu, H., Lu, H., Ye, F.Q., Stein, E.A. and Yang, Y. Noninvasive Quantification of Cerebral Blood Volume in Humans during Functional Activation. NeuroImage 30: 377-387, 2006.

15. Lu, H., Jensen, J.H., Ramani, A., and Helpern, J.A. Three-dimensional Characterization of Non-Gaussian Water Diffusion in Humans using Diffusion Kurtosis Imaging. NMR in Biomedicine 19: 236-247, 2006.

16. Jensen, J.H., Chandra, R., Helpern, J.A., Ramani, A., Lu, H., Johnson, G., Lee, S.P., and Kaczynski, K. Magnetic Field Correlation Imaging. Magnetic Resonance in Medicine 55: 1350-1361, 2006.

17. Strouse, J.J., Cox, C., Melhem, E., Lu, H., Kraut, M., Razumovsky, A., Yohay, K., van Zijl, P.C., Casella, J.F. Inverse Correlation Between Cerebral Blood Flow and Neurocognitive Function in Children with Sickle Cell Anemia (SCA). Blood 108: 379-381, 2006.

18. Lu, H., Donahue, M.J., and van Zijl, P.C. Detrimental Effects of BOLD Signal in Arterial Spin Labeling fMRI at High Field Strength. Magnetic Resonance in Medicine 56: 546-552, 2006.

19. Donahue, M.J., Lu, H., Jones, C.K., Pekar, J.J., and van Zijl, P.C. An Account of the Discrepancy between MRI and PET Cerebral Blood Flow Measures: A High-field MRI Investigation. NMR in Biomedicine 19: 1043-1054, 2006.

20. Donahue, M.J., Lu, H., Jones, C.K., Pekar, J.J., and van Zijl, P.C. An Investigation of the VASO Contrast Mechanism Reveals a Novel Method for Quantifying Cerebral Blood Flow. Magnetic Resonance in Medicine 56: 1261-1273, 2006.

21. Jensen, J.H., Lu, H., and Inglese, M. Microvessel Density Estimation in Human Brain by Means of Dynamic Contrast-Enhanced Echo Planar Imaging. Magnetic Resonance in Medicine 56: 1145-1150, 2006.

22. Prabhakaran, V., Raman, S., Grunwald, M., Mahadevia, A., Hussain, N., Lu, H., van Zijl, P.C., Hillis, A.E. Neural substrates of word generation during stroke recovery: the influence of cortical hypoperfusion. Behavioral Neurology 18: 45-52, 2007.

23. Thakur, P.H., Lu, H., Hsiao, S.S., Johnson, K.O. Automated optimal detection and classification of neural action potentials in extra-cellular recordings. J Neurosci Methods 162(1-2):364-76 2007.

24. Ge, Y., Jensen, J.H., Lu, H., Helpern, J.A., Miles, L., Inglese, M, Babb, J., Herbert, J., Grossman, R. Quantitative Assessment of Iron Accumulation in the Deep Gray Matter of Multiple Sclerosis by Magnetic Field Correlation Imaging. American Journal of Neuroradiology AJNR 28: 1639-1644, 2007.

25. Lu, H., Law, M., Hesseltine, S.M., Rapalino, O., Ge, Y., Jensen, J.H., and Helpern, J.A. Quantitative Measurement of Spinal Cord Blood Volume in Humans using Vascular-Space-Occupancy MRI, NMR in Biomedicine, 21: 226-232, 2008.

26. Lu, H., Pollack, E., Young, R., Babb, J. Johnson, G., Jensen, J.H., Helpern, J.A., and Law, M. Predicting Grade of Cerebral Glioma using Vascular-Space-Occupancy MRI, American Journal of Neuroradiology AJNR, 29: 373-378, 2008.

27. Newsome, M.R., Steinberg, J.L., Scheibel, R.S., Troyanskaya, M., Chu, Z., Hanten, G., Lu, H., Lane, S., Lin, X., Hunter, J.V., Vasquez, C., Zientz, J., Li, X., Wilde, E.A., and Levin, H.S. Effects of traumatic brain injury on working memory-related brain activation in adolescents, Neuropsychology 22: 419-425, 2008.

28. Lu, H., and Ge, Y. Quantitative evaluation of cerebral venous oxygenation using T2-Relaxation-Under-Spin-Tagging (TRUST) MRI, Magnetic Resonance in Medicine, 60: 357-363, 2008.

29. Lu, H., Zhao, C., Ge, Y., and Lewis-Amezcua, K. Baseline blood oxygenation modulates response amplitude: physiologic basis for inter-subject variations in fMRI signals, Magnetic Resonance in Medicine, 60: 364-372, 2008.

30. Lin, A.L., Fox, P.T., Yang, Y., Lu, H., Tan, L.H., and Gao, J.H. Evaluation of MRI Models in the Measurement of CMRO2 and its Relationship with CBF. Magnetic Resonance in Medicine, 60:380-389, 2008.

31. Lu, H., and Yang, Y. Neuroimaging Methods Using Nuclear Magnetic Resonance. In “Neurobiology of Mental Illness”, Eds. Charney and Nestler. Oxford Press, 2008.

32. Lin, A.L., Fox, P.T., Yang, Y., Lu, H., Tan, L.H., and Gao, J.H. Time-dependent Correlation of Cerebral Blood Flow with Oxygen Metabolism in Activated Human Visual Cortex as Measured by fMRI, NeuroImage, 44:16-22, 2009.

33. Jensen, J.H., Szulc, K., Hu, C., Ramani, A., Lu, H., Xuan, L., Falangola, M.F., Chandra, R., Knopp, E., Schenck, J., Zimmerman, E.A., Helpern, J.A. Magnetic Field Correlation as a Measure of Iron-Generated Magnetic Field Inhomogeneities in the Brain, Magnetic Resonance in Medicine, 61:481:485, 2009.

34. Uh, J., Lewis-Amezcua, K., Varghese, R., Lu, H. On the measurement of absolute cerebral blood volume using Vascular-Space-Occupancy MRI, Magnetic Resonance in Medicine, 61: 659-667, 2009.

35. Uh, J., Lewis-Amezcua, K., Martin-Cook, K., Cheng, Y., Weiner, M., Diaz-Arrastia, R., Devous, M., Shen, D., Lu, H. Cerebral Blood Volume in Alzheimer's Disease and Correlation with Tissue Structural Integrity, Neurobiology of Aging, In-press.

36. Xu, F., Ge, Y., Lu, H. Non-invasive Quantification of Whole-brain Cerebral Metabolic Rate of Oxygen by MRI, Magnetic Resonance in Medicine, In-press.

37. Yezhuvath, U., Lewis-Amezca, K. Varghese, R., Xiao, G., Lu, H. On the assessment of cerebrovascular reactivity using hypercapnia BOLD MRI, NMR in Biomedicine, In-press.

Publications

UT Southwestern Medical Center

Laboratory of Functional Magnetic Resonance Imaging