The Alto lab is studying the molecular mechanisms of bacterial toxins and effector proteins and we specifically examine how these proteins hijack human intracellular signal transduction cascades.   We take a multidisciplinary approach from protein biochemistry and structural biology to reconstitution studies and live cell imaging.  Thus, our major goal is to gain key molecular insights that may reveal new leads into drug development and future treatments of important human infectious diseases.

‘Host-pathogen interactions from atoms to biology’