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UT Southwestern Medical Center

The Altschuler & Wu Computational and Systems Biology Laboratory

Current Lab Members (details)


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Jayant Avva, Ph.D.
Postdoctoral Researcher

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Jayant joins the lab with a PhD in Electrical Engineering with a focus on Systems Biology from Case Western Reserve University. He is involved in an exciting new project that involves tissue image analysis. In his spare time he reads comics, does yoga and pretends to be super busy.
Kathy M. Boness, Ph.D.
Postdoctoral Researcher

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Human Lung Cancer: Tissue Heterogeneity
Dhruba Deb ( ধ্রুব দেব )
Graduate Student

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After earning his B.Sc. in Biotechnology with Chemistry and Microbiology double minors and his M.Sc. in Bioinformatics, Dhruba worked at the Indian Institute of Science to gather experience in understanding protein structures from a network percolation perspective. As a graduate student, he is interested in the correlation of signaling state heterogeneity with drug response in cancer cells. Dhruba likes to dance hip-hop, swim and paint during his spare time.
Adam Coster
Graduate student

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Adam left the rolling corn fields of Iowa to get a B.A. in Biology at the University of Chicago, where he developed a love for both teaching and high-throughput drug screening. Following another round of drug screen development at Washington University in St Louis, Adam began his graduate career at UT Southwestern, where he hopes to inhabit a midpoint between biology and computer science. He is currently developing novel reagents and software for the exploration of the cell-cycle dependence of, and cross-talk between, dynamic protein networks.
Chin-Jen (Jeremy) Ku, Ph.D.
Research Scientist

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Chin-Jen (Jeremy) holds M.S. and Ph.D. degrees in Electrical and Computer Engineering from Cornell University with research experiences spanning optimization, statistical signal processing and machine learning. Dr. Ku now combines his expertise in mathematical modeling and software development to study the design principles of complex biological systems at the single cell level. He likes playing tennis and guitar during his free time.

Jungseog Kang (강정석), Ph.D.
Assistant Instructor

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Jungseog obtained his PhD in Biology in the University of Texas at Austin and received postdoctoral training in Hongtao Yu lab at Southwestern medical center. He is currently studying heterogeneity of cancer cells upon drug response. He likes to play wii games with his kids in his free time.
Shanshan Liu (姗姗 刘), Ph.D.
Postdoctoral Researcher

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Shanshan received her Ph.D. in Cancer Biology from Vanderbilt University, where she studied the role played by extracellular matrix proteins in cancer progression. She is interested in heterogeneity of cancer cell populations in vivo. In her spare time, she enjoys reading, games and shopping.


Nuno Lages, Ph.D.
Postdoctoral Researcher

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Nuno received his Ph.D. degree in Biochemistry from the University of Lisbon, Portugal, where he combined computational and experimental approaches to discriminate between enzyme kinetic models. Presently, Nuno is interested in studying mechanisms of drug resistance in model organisms. He likes reading, traveling and discovering new music in his free time.
Kathleen Lyons
Lab Manager

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Kathy brings an unusual combination of restaurant entrepreneurship and clinical studies to lab. Her BS in Medical Technology and extensive Restaurant background enables her to help keep the lab running smootly while working on various projects. Outside the lab, you can find Kathy rescuing retired greyhounds.


Nicholas Norris
Graduate Student

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Nick originally hails from the beaches of Southern California. He earned his B.S. in Cellular and Molecular Biology from The Master's College, and is interested in the hormonal regulation of glucose metabolism. An amateur powerlifter, Nick also enjoys cooking, camping, and a well made cup of coffee.
Benjamin Pavie
Research assistant II

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Benjamin Pavie comes to the lab with a background in Biology and computer science. He obtained his master in Fundamental Virology at the Pasteur Institute / UPMC in Paris (France) and a degree in Java and DataBase at UVSQ, France. Benjamin develops computational infrastructure at the interface between experiment and analysis. In his spare time he enjoys reading and traveling.
Satwik Rajaram (सात्विक राजाराम), Ph.D.
Postdoctoral Researcher

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Satwik received his Ph.D in Physics from the University of Illinois at Urbana-Champaign. He brings with him experience in bioinformatics, particularly in the context of variability in gene expression. Satwik would like to better understand the significance of such variability in the context of microscopy. Presently he is developing the framework for the next generation of image analysis tools for our lab. In his free time Satwik enjoys reading, listening to music and spending time with cats.
Robert (Joey) Steininger III
Graduate Student

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Joey, a native of Cambridge, Massachusetts, earned his S.B. in Chemical Engineering with a minor in Chemistry from M.I.T. As a graduate student, he hopes to use his engineering and biological training to understand biological systems and their responses to perturbations. In his spare time, Joey likes to play volleyball and piano.
Curtis Andrew Thorne, Ph.D.
Postdoctoral Researcher

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Curtis received his Ph.D. in Cell and Developmental Biology from Vanderbilt University, where he took a chemical biology and systems-level approach to understanding Wnt signal transduction. His obsession with quantifying cellular events and understanding the structure of signaling pathways lead him to the Altschuler and Wu lab. Now Curtis is studying the physiological role of non-genetic cellular heterogeneity in development and cancer. In his free time, Curtis enjoys playing the guitar, canoeing, BBQing and doing anything with his lovely wife and son.
Yanqin Wang, Ph.D.
Postdoctoral Researcher

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Yanqin received her Ph.D. degree in Microbiology from the University of Texas at Austin, where she studied chemotaxis in Dictyostelium. She joined the Altschuler and Wu Lab to continue working on chemotaxis and other processes related to human diseases via computational modeling and molecular biology approaches. During her free time, she likes shopping, reading, and dreaming about the novels she will write one day.
Chonlarat (Pearl) Wichaidit (ชลรัตน์ วิชัยดิษฐ), Ph.D.
Postdoctoral Researcher

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Chonlarat has a Ph.D. in Electrical and Computer Engineering from the University of Wisconsin at Madison . After obtaining her Ph.D., she worked on problems in electromagnetics and plasma before joining the Altschuler and Wu laboratory. She has been fascinated by biology and wishes to apply her computational and analysis skills to understand biological phenomena.
Qi Wu (齊屋)
Research assistant II

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I received my Masters degree in Immunology and Virology from the University of Massachusetts Medical School where I studied antigen cross-prestation pathways in dendritic cells. After graduation, I worked on protein expression, monoclonal antibody generation. Now, I am excited to be working on the development of cell imaging assays and quantitative processing of those beautiful images. In my spare time, I like photography, movie, BBQ and playing with my son.