2006 2007 2008 2009 2010 2011 2012

Alternative splicing regulation of
telomerase: a new paradigm?

Trends in Genetics 1137: 1-9 (2014)

Regulation of human telomerase splicing
by RNA:RNA pairing

Nature Communications DOI: 10.1038/ncomms4306 (2014)

Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer
Clinical Cancer Research doi: 10.1158/1078-0432.CCR-13-2589 (2014)

Are Short Telomeres Hallmarks of Cancer Recurrence?
Clinical Cancer Research 20(4): 779-781 (2014)

Determining if Telomeres Matter in Colon Cancer Initiation or Progression
JNCI 105(16): 1166-1168 (2013)

Are Short Telomeres Predictive of Advanced Cancer?
Cancer Discovery 3: 1096-1098 (2013)

Facioscapulohumeral muscular dystrophy
Are telomeres the end of the story?
Rare Diseases 1: e26142-1-e26142-5 (2013)

Mitigation of Radiation-Induced Damage by Targeting EGFR in Noncancerous Human Epithelial Cells
Radiation Research180: 259–267 (2013)

Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations
Mol Cancer Res: 11(6): 638-650 (2013)

Telomere position effect regulates DUX4 in human facioscapulohumeral muscular dystrophy
Nature Structural & Molecular Biology 20(6): 671-678 (2013)

Progenitor Cell Line (hPheo1) Derived from a Human Pheochromocytoma Tumor
PLOS 8(6): e65624 (2013)

Regulation of Telomerase Alternative Splicing:
A Target for Chemotherapy
Cell Reports 3: 1028–1035 (2013)

A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer
Clinical Cancer Research 19: 2061-2070 (2013)

Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation
Oncogene 32: 3139–3146 (2013)

Histone Modifications and DNA Double-Strand Break Repair after Exposure to Ionizing Radiations
Radiation Research 179: 383-392 (2013)

Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton
International Journal of Oncology 42: 1709-1715 (2013)

The Roles of Telomerase in the Generation of Polyploidy during Neoplastic Cell Growth
Neoplasia 15(2): 156-168 (2013)

Identification of novel driver tumor suppressors through functional interrogation of putative passenger mutations in colorectal cancer
International Journal of Cancer 132: 732–737 (2013)

Cancer and Telomeres--An ALTernative to Telomerase
Science 336: 1388-1390 (2012)

RNAi screening of the human colorectal cancer genome identifies multifunctional tumor suppressors regulating epithelial cell invasion
Cell Research 22(11): 1605-1608 (2012)

Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation
PNAS (2012)

Early and late steps in telomere overhang
processing in normal human cells: the
position of the final RNA primer drives
telomere shortening
Genes & Development 26: 1167–1178 (2012)

Is telomerase a viable target in cancer?
Mutation Research 730: 90-97 (2012)

Short Hairpin RNA Screen Indicates That Klotho Beta/FGF19 Protein Overcomes Stasis in Human Colonic Epithelial Cells
The Journal of Biological Chemistry 286(50): 43294–43300 (2011)

Role of telomeres and telomerase in cancer
Semin Cancer Biol (2011)

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination
Aging Cell 10: 761–768 (2011)

Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth
Cancer Research 71(13); 4359-4365 (2011)

Multipotent Capacity of Immortalized Human Bronchial Epithelial Cells
PLOS 6(7); 1-8 (2011)

Processive and Distributive Extension of Human Telomeres by Telomerase under Homeostatic and Nonequilibrium Conditions
Molecular Cell 42: 297–307 (2011)

Characterization of Aneuploid Populations with Trisomy 7 and 20 Derived from Diploid Human Colonic Epithelial Cells
Neoplasia 13(4): 348-357 (2011)

Telomeres and telomerase in normal and cancer stem cells
FEBS Letters 584: 3819–3825 (2010)

CDDO-Me Protects against Space Radiation-Induced Transformation of Human Colon Epithelial Cells
Radiation Research 174: 27–36 (2010)

The effects of telomerase inhibition on prostate tumor-initiating cells
Int. J. Cancer: 127: 321–331 (2010)

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro
Gastroenterology 138: 1010-1021 (2010)

DNA damage intensity in fibroblasts in a 3-dimensional collagen matrix correlates with the Bragg curve energy distribution of a high LET particle
Int. J. Radiat. Biol. 86(3): 194–204 (2010)

Differential Inhibition of Protein Translation Machinery by Curcumin in Normal, Immortalized, and Malignant Oral Epithelial Cells
Cancer Prevention Resarch 3(3): 1-8 (2010)

Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy
Cancer Metastasis Rev 29: 61-72 (2010)

The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth
Clinical Cancer Research 16(1): 154-163 (2010)

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians
PNAS (107): 1710-1717 (2010)

H-Ras Expression in Immortalized Keratinocytes Produces an Invasive Epithelium in Cultured Skin Equivalents
PLoS ONE 4(11) (2009)

Antitumor Activity of a Novel Antisense Oligonucleotide Against Akt1
Journal of Cellular Biochemistry 108: 832–838 (2009)

Is Telomerase a Novel Target for Metastatic Colon Cancer?
Current Colorectal Cancer Reports 5: 203–208 (2009)

Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas
J Bone Joint Surg Am 91: 928-937 (2009)

Telomere length regulates ISG15 exression in human cells
Aging 1(7); 608-621 (2009)

Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells
Cell 138; 463–475 (2009)

Prostate tumor-initiating cells: A new target for telomerase inhibition therapy?
Biochimica et Biophysica Acta 1792: 289–296 (2009)

Pancreatic cancer stem cells: Fact or fiction?
Biochimica et Biophysica Acta 1792; 248–259 (2009)

Altered States of Telomere Deprotection and the Two-Stage Mechanism of Replicative Aging
Molecular and Cellular Biology 29(9): 2390–2397 (2009)

A case study of ‘‘disorganized development’’ and its possible relevance to genetic determinants of aging
Mechanisms of Ageing and Development 130: 350–356 (200))

Two- and Three-Dimensional Models for Risk Assessment of Radiation-Enhanced Colorectal Tumorigenesis
Radiation Research 171; 33-40 (2009)

SGNP: An Essential Stress Granule/Nucleolar Protein Potentially Involved in 5.8s rRNA Processing/Transport
PLoS ONE 3(11): 1-8 (2008)

Inhibition of Telomerase Activity Enhances Hyperthermia- Mediated Radiosensitization
Cancer Research 68(9): 3370-3378 (2008)

In Vivo and In Vitro Effects of a HIF-1a Inhibitor, RX-0047
Journal of Cellular Biochemistry 104: 985–994 (2008)

Actions of human telomerase beyond telomeres
Cell Research 18: 725-732 (2008)

Targeting telomerase for cancer therapeutics
British Journal of Cancer 98(4): 677-683 (2008)

Telomere Dynamics in Macaques and Humans
Journal of Gerontology: BIOLOGICAL SCIENCES 62A(4): 367–374 (2007)

Immortalization of epithelial progenitor cells mediated by resveratrol
Oncogene 1–10 (2007)

Human diseases of telomerase dysfunction: insights into tissue aging
Nucleic Acids Research 1-11 (2007)

Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells
Drug Discovery Today 12(15/16): 611-621 (2007)

Tissue Culture as a Hostile Environment: Identifying Conditions for Breast Cancer Progression Studies
Cancer Cell 12: 100-101 (2007)

Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclindependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies
Aging Cell online (2007)

Adult-onset pulmonary fibrosis caused by mutations in telomerase
PNAS 104(18); 7552-7557 (2007)

Antiadhesive Effects of GRN163L—An Oligonucleotide N3' P5' Thio-Phosphoramidate Targeting Telomerase
Cancer Research 67(3): 1121-1129 (2007)

Hallmarks of telomeres in ageing research
Journal of Pathology 211: 114-123 (2007)

Inexpensive low-oxygen incubators
Nature Protocols 1(4): 2088-2090 (2006)

Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol
Nature Protocols 1(3): 1583-1590 (2006)

Telomerase therapeutics for cancer: challenges and new directions
Nature Reviews Drug Discovery (online) 2006

POT1 protects telomeres from a transient DNA
damage response and determines how human
chromosomes end

The EMBO Journal 24: 2667-2678 (2006)

Time, tumours and telomeres Meeting on Cancer and Aging
EMBO Reports 7(5): 479-483 (2006)

A three-dimensional model of differentiation of immortalized human bronchial epithelial cells
Differentiation 74: 141-148 (2006)

Multiple Oncogenic Changes (K-RASV12, p53 Knockdown, Mutant EGFRs, p16 Bypass, Telomerase) Are Not Sufficient to Confer a Full Malignant Phenotype on Human Bronchial Epithelial Cells
Cancer Research 66(4):. 2116-2128 (2006)

Human Telomeres Have Different Overhang Sizes at Leading versus Lagging Strands
Molecular Cell 21: 427–435 (2006)

The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres
EMBO reports 7: 225–230 (2006)

Use of Telomerase to Create Bioengineered Tissues
Ann. N.Y. Acad. Sci. 1057: 479–491 (2005).

Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer
Breast Cancer Research and Treatment
DOI 10.1007/s10549-005-9043-5 (2005)

Telomere Biology in Aging and Cancer
Journal of the American Geriatrics Society 53 S292-S294 (2005)

Fine-Tuning the Chromosome Ends
The Last Base of Human Telomeres

Cell Cycle 4(11) 108-111 (2005)

In vivo Inhibition of Lung Cancer by GRN163L: A Novel Human Telomerase Inhibitor
Cancer Research 65(17) 7866-7873 (2005)

Function of AP-1 in Transcription of the Telomerase Reverse Transcriptase Gene (TERT) in Human and Mouse Cells
Molecular and Cellular Biology 25(18) 8037–8043 (2005)

BRAF(E600)-associated senescence-like cell cycle arrest of human naevi
Nature 436(4) 720-724 (2005)

Telomerase as a therapeutic target in cancer
Drug Discovery Today: Disease Mechanisms 2 (2) 159-164 (2005)

Lipid modification of GRN163, an N30'-P50; thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition
Oncogene Short Report 1–7 (2005)

Lagomorphs (rabbits, pikas and hares) do not use
telomere-directed replicative aging in vitro

Mechanisms of Ageing and Development 126; 685–691 (2005)

The Longevity Gender Gap: Are Telomeres the Explanation?
Sci. Aging Knowl. Environ. 2005(23) (2005)

Meeting Report: The Role of Telomeres and Telomerase in Cancer
Cancer Research 65(9); 3513-3517 (2005)

Telomere-End Processing: the Terminal Nucleotides of Human Chromosomes
Molecular Cell 18; 131–138 (2005)

Shared Phenotypes Among Segmental Progeroid Syndromes Suggest Underlying Pathways of Aging
Journal of Gerontology: BIOLOGICAL SCIENCES 60A(1); 10-20 (2005)

Telomere-binding factors and general DNA repair
Nature Genetics 37(2); 116-118 (2005)

Human Telomeres Maintain Their Overhang Length at Senescence
Molecular and Cellular Biology 25(6); 2158-2168 (2005)

Does Telomerase Moonlight?
The Scientist 19(4); 18-19 (2005)

Characterization of Growth and Differentiation in a Telomerase-Immortalized Human Corneal Epithelial Cell Line
Investigative Ophthalmology & Visual Science 46(2); 470-8 (2005)

Mechanism-based combination telomerase inhibition therapy
Cancer Cell 7; 1--2 (2005)

Senescence and immortalization: role of telomeres and telomerase
Carcinogenesis 26(5); 867-874 (2005)

Immortalization of Human Bronchial Epithelial Cells in the Absence of Viral Oncoproteins
Cancer Research 64; 9027–9034 (2004)

Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions
Oncogene 23; 6193–6198 (2004)

Analysis of Mammalian Telomere Position Effect
Methods Mol Biol. 287; 121-136 (2004)

Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes
PNAS 101(35); 12928–12933 (2004)

A Reproducible Laser-Wounded Skin Equivalent Model to Study the Effects of Aging In Vitro
Rejuvenation Research 7(2); 99-110 (2004)

Does a Sentinel or a Subset of Short Telomeres Determine Replicative Senescence?
Molecular Biology of the Cell 15; 3709–3718 (2004)

The Frequency of Homologous Recombination in Human ALT Cells
Cell Cycle 3(5); 547-549 (2004)

Telomeres Are Double-Strand DNA Breaks Hidden from DNA Damage Responses
Molecular Cell 14(4); 420-421 (2004)

Telomeric Recombination in Mismatch Repair Deficient Human Colon Cancer Cells after Telomerase Inhibition
Cancer Research 64; 3444–3451 (2004]

Telomeres in dyskeratosis congenita
Nature Genetics 36(5); 437-438 (2004)

Hallmarks of senescence in carcinogenesis and cancer therapy
Oncogene 23; 2919–2933 (2004)

Modification of Subtelomeric DNA
Molecular and Cellular Biology 24(10); 4571-4580 (2004)

Spontaneous Immortalization of Clinically Normal Colon-Derived Fibroblasts from a Familial Adenomatous Polyposis Patient
Neoplasia 6(3); 265–272 (2004)

Spontaneous reactivation of a silent telomeric transgene in a human cell line
Chromosoma 112; 240–246 (2004)

Analysis of Telomeres and Telomerase
UNIT 18.6 Analysis of Telomeres and Telomerase (2003)

Differential Gene Expression Profiles Between Neuroblastomas With High Telomerase Activity and Low Telomerase Activity
Journal of Pediatric Surgery 38 (12); 730-1734 (2003)

Homologous Recombination in Human Telomerase-Positive and ALT Cells Occurs With the Same Frequency
EMBO reports 4(12); 1138-1143 (2003)

Telomerase Therapeutics: Telomeres Recognized as a DNA
Damage Signal

Clinical Cancer Research 9(10); 3521–3525 (2003)

Developmental Differences in the Immortalization of Lung Fibroblasts by Telomerase
Aging Cell 2(5); 1-9 (2003)

Telomere Dysfunction: A Potential Cancer Predisposition Factor
Journal of the National Cancer Institute, 95(16); 1211-1218 (2003)

Myofibroblast Differentiation of Normal Human Keratocytes and hTERT, Extended-Life Human Corneal Fibroblasts
Investigative Ophthalmology & Visual Science 44(5);1850-1858 (2003)

A Peroxisome Proliferator-activated Receptor-gamma Agonist and the p53 Rescue Drug CP-31398 Inhibit the Spontaneous Immortalization of Breast Epithelial Cells
Cancer Research 63; 1914–1919 (2003)

Characterisation of telomerase immortalised normal human oesophageal squamous cells
Gut 52; 327-333 (2003)

Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells
Oncogene 22; 433–444 (2003)

Human Telomerase Can Immortalize Indian Muntjac Cells
Experimental Cell Research 281; 63–76 (2002)

p16INK4a inactivation is not required to immortalize human mammary epithelial cells
Oncogene 21; 7897–7900 (2002)

Is There an "Anti-aging" Medicine?
International Longevity Center - USA
Journal of Gerontology: BIOLOGICAL SCIENCES 57A (9); B333-B338 (2002)

Telomerase:A target for cancer therapeutics
Cancer Cell 2; 257-265 (2002)

Human Ku70/80 Associates Physically with Telomerase through Interaction with hTERT
The Journal of Biological Chemistry 277 (49);47242–47247 (2002)

Human Telomerase and Its Regulation
Microbiology and Molecular Biology Reviews 66(3); 407–425 (2002)

Telomerase Immortalization of Human Myometrial Cells
Biology of Reproduction 67; 506–514 (2002)

Historical claims and current interpretations of replicative aging
Nature Biotechnology 20; 682-688 (2002)

Telomerase in cancer and aging
Critical Reviews in Oncology/Hematology 41; 29-40 (2002)

Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
Differentiation 69; 188–197 (2002)

Oligonucleotide N3'–›P5' phosphoramidates as efficient telomerase inhibitors
Oncogene 21; 638-642 (2002)

A model for heterogeneous nuclear ribonucleoproteins in telomere and telomerase regulation
Oncogene 21; 580-583 (2002)

Telomere Biology and Cellular Aging in Nonhuman Primate Cells
Experimental Cell Research 272; 146–152 (2002)

Telomerase regulation: not just flipping the switch
Current Opinion in Genetics & Development 12; 80–85 (2001)

Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells
Nucleic Acids Research 29(23); 4818-4825 (2001)

Telomerase inhibitors -- Oligonucleotide phosphoramidates as potential therapeutic agents
Nucleosides, Nucleotides & Nucleic Acids 20(4–7); 401–410 (2001)

Treatment of Malignant Glioma Cells with the Transfer of Constitutively Active Caspase-6 Using the Human Telomerase Catalytic Subunit (Human Telomerase Reverse Transcriptase) Gene Promoter
Cancer Research 61; 5796-5802 (2001)

Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells
Mechanisms of Ageing and Development 122; 1685-1694 (2001)

Telomerase Can Inhibit the Recombination-based Pathway of Telomere Maintenance in Human Cells
The Journal of Biological Chemistry 276(34); 32198-32203 (2001)

Immunohistochemical Detection of Telomerase (hTERT) Protein in Human Cancer Tissues and a Subset of Cells in Normal Tissues
Neoplasia 3(1); 17-26 (2001)

The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo
RNA 7; 1068-1075 (2001)

Telomere Position Effect in Human Cells
Science 292: 2075-2077 (2001)

Telomeresand Telomerase: Implications for Cancer and Aging
Radiation Research 155:188–193 (2001)

Characterization of ataxia telangiectasis fibroblasts with extended life-span through telomerase expression
Oncogene 20:278-288 (2001)

Telomerase and cancer
Human Molecular Genetics 10(7) 677-685 (2001)

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
Genes and Development 15:398-403 (2001)

Telomerase and breast cancer
Breast Cancer Research 3:146-149 (2001)

Telomerase inhibitors
TRENDS in Biotechnology 19(3):114-120 (2001)

Immortalizing Human Cells with Telomerase

When Do Telomeres Matter?
Science 291:839-840 (2001)

Cellular senescence as a tumor-protection mechanism: the essential role of counting
Current Opinions in Genetics and Development 11:98-103 (2001)

Effects of Chemopreventive and Antitelomerase Agents on the Spontaneous Immortalization of Breast Epithelial Cells
Journal of National Cancer Institute 93(1):39-45 (2001)

Ageing and cancer: the telomere and telomerase connection
Novartis Foundaton Symposium (2001)

An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity
Neoplasia 2(5):433-440 (2000)

Heterogeneous Nuclear Ribonucleoproteins C1 and C2 Associate with the RNA Component of Human Telomerase
Molecular and Cellular Biology 20(23): 9084-9091 (2000)

Hayflick, his limit, and cellular ageing
Nature 1:72-76 (2000)

Telomere Dynamics in Cells with Introduced Telomerase: A Rapid Assay for Telomerase Activity on Telomeres
Molecular Cell Biology Research Communications 3:312-318 (2000)

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology
Nature Medicine 6(8):849-851 (2000)

Transient Expression of Human Telomerase Extends the Life Span of Normal Human Fibroblasts
Biochemical and Biophysical Research Communications 273:1095-1098 (2000)

Implications of mapping the human telomerase gene (hTERT) as the most distal gene on chromosome 5p
Neoplasia 2(3):195-196 (2000)

Telomere shortening is proportional to the size of the 3' G-rich telomeric overhang
The Journal of Biological Chemistry 275(26):19719-19722 (2000)

Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
The Journal of Biological Chemistry 275(14):10072-10076 (2000)

The establishment of telomerase-immortalized cell lines representing human chromosome instability syndrome
Human Molecular Genetics 9(3):403-411 (2000)

The use of telomerized cells for tissue engineering
Nature Biotechnology 18:22-23 (2000)

Cancer Research, An Encylopedic Reference 880-886 (1999)

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
PNAS 96(25):14276-14281 (1999)

At the end of the millennium, a view of the end
Nature Genetics 23:382-383 (1999)

Mutant dyskerin ends relationship with telomerase
Science 286:2284-2285 (1999)

Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro
Molecular and Cellular Biology 19(9):6207-6216 (1999)

Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels
Molecular and Cellular Biology 19(6):3989-3997 (1999)

Functional requirement of p23 and Hsp90 in telomerase complexes
Genes and Development 13:817-826 (1999)

Telomeres and telomerase in the regulation of human cellular aging
Molecular Biology of Aging: Alfred Benzon Symposium 44: 148-158 (1999)

Toward identifying a cellular determinant of telomerase repression
Journal of the National Cancer Institute 91(1): 4-9 (1999)

Telomerase activity does not always imply telomere maintenance
Biochemistry and Biophysics Research Communications 254:795-803 (1999)

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
Nature Genetics 21:115-118 (1999)

Characterization of Paired Tumor and Non-Tumor Cell Lines Estaablished from Patients with Breast Cancer
Int. J. Cancer 78, 766–774 (1998)

In situ hybridization for telomerase RNA in routine cytologic brushings for the diagnosis of pancreaticobiliary malignancies
Gastrointestinal Endoscopy 48(4); 402-405 (1998)

Telomerase Activity in Lung Cancer Cells Obtained from Bronchial Washings
Journal of the National Cancer Institute
90(9); 684-690 (1998)

Extension of life-span by introduction of telomerase into normal human cells
Science 279: 349-353 (1998)

Telomerase Activity Is Detected in Pancreatic Cancer but not in Benign Tumors
Cancer Research 57: 326-331 (1997)

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
Nature Genetics 17: 498-502 (1997)

A Survey of Telomerase Activity in Human Cancer
European Journal of Cancer 33(5):787-791 (1997)

Regulation of telomerase activity in immortal cell lines
Molecular and Cellular Biology 16(6):2932-2939 (1996)

Refining the telomere-telomerase hypothesis of aging and cancer
Nature Biotechnology 14 836-839 (1996)

Telomerase Activity in Human Germline and Embryonic Tissues and Cells
Developmental Genetics 18: 173-179 (1996)

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?
Trends in Cell Biology 5: 293-297 (1996)

Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)
Methods in Cell Science 17; 1-15 (1995)

Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity
Nucleic Acids Research 23(18); 3794-3795 (1995)

Correlating telomerase activity levels with human neuroblastoma outcomes
Nature Medicine 1(3); 249-255 (1995)

Telomerase Activity in Small-Cell and Non-Small-
Cell Lung Cancers

Journal of the National Cancer Institute 87(12); 895-902 (1995)

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
Science 266: 2011-2015 (1994)

The Frequency of Imoortalization of Human Fibroblasts and Mammary Epithetiial Cells Transfected with SV40 Large T-Antigen
Experimental Cell Research 209: 45-52 (1993)

Defining the molecular mechanisms of human cell immortalization
Biochimica et Biophysica Acta 1072: 1-7 (1991)