Xiuhua Dong, Ph.D.

Education and Training

• Shandong Medical University, Jinan, China, Bachelor of Clinical Medicine, 1999
• Shandong Academy of Medical Sciences, Jinan, China, M.S., Immunology, 2002
• Peking Union Medical College/Tsinghua University, Beijing, China,Ph.D., Biochemistry and Molecular Biology, 2006

Positions

• 2007 - present, Postdoctoral Researcher, UT Southwestern Medical Center

Honors and Awards

• Mathilde Krim Fellowship for AIDS Research, 2010

Publications

1. Dong X., Biswas A., Süel K. E., Jackson L. K., Martinez R., Gu H. and Chook Y. M. Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature, 2009, 458 (7242): 1136-1141.
2. Dong, X., Biswas, A. & Chook, Y. M. Structural basis of assembly and disassembly of the CRM1 nuclear export complex. Nat. Struct. Mol. Biol. 2009, 16 (5): 558-560.
3. Dong X., Xu F., Gong Y., Gao J., Lin P., Chen T., Peng Y., Qiang B., Yuan J., Peng X. & Rao Z. Crystal structure of the V domain of human Nectin-like molecule-1/SynCAM3/TSLL1/IGSF4B, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule. Journal of Biological Chemistry, 2006, 281 (15): 10610-10617.
4.  Dong X., Peng Yong, Peng Ying, Xu F., Qiang B., Yuan J. & Rao Z. Characterization   and crystallization of human DPY-30-like protein, an essential component of dosage compensaton complex. Biochimica et Biophysica Acta-Proteins & Proteomics 2005, 1753(2):257-62.
5. Fan Z., Peng K., Tan X., Yin B,. Dong X., Qiu F., Shen Y., Wang H., Yuan J., Qiang B. & Peng X. Molecular cloning, expression, and purification of SARS-CoV nsp13. Protein Expression Purification. 2005, 41(2):235-40.
6. Wen Z., Di W., Dong X., Yin B., Qiang B., Yuan J., Peng X. Expression of HRV 14 3C protease in E.coli and its cleavage activity analysis.  Basic Medical Sciences and Clinics (in Chinese). 2005. 25(7): 653-657.
7. Dong X., Zhao Y. Cloning of human leptin gene and its expression in COS-7 cells. Chinese Journal of Endocrinology and Metabolism (in Chinese). 2003. 19 (2): 136-138.   
8. Dong X., Zhao Y. Preparation and preliminary application of monoclonal antibody against human Leptin. Journal of Cell Biology (in Chinese). 2002. 24 (3): 182-185.
9. Dong X., Zhao Y.. Research progress of Leptin in adolescence (review). Foreign Medicine Sciences. Family Planning Fascicule (in Chinese). 2002, 21(1).
10. Dong X., Zhao Y. The function of Leptin in obesity (review). Foreign Medicine Sciences. Endocrinology Fascicule (in Chinese), 2002.
11. Li C., Zhang S., Dong X. The treatment of amniotic fluid embolism. Journal of Linyi Medical College (in Chinese).  2002, 24(5).

Contact

• Xiuhua.Dong@UTSouthwestern.edu
  214-645-6168