Selected publications

  1. Liu ML, Zang T, Zhang CL*. Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients. Cell Rep. 2015 Dec 22. pii: S2211-1247(15)01431-X. doi: 10.1016/j.celrep.2015.12.018. [Epub ahead of print] PMID: 26725112. News reported in Healthcanal, MDLinx, Alzforum, The ALS Forum, Science Mission, ALS News Today, etc.

  2. Islam MM, Smith DK, Niu W, Fang S, Iqbal N, Sun G, Shi Y, Zhang CL*. Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming. Stem Cell Reports. 2015.

  3. Niu W, Zang T, Smith DK, Vue TY, Zou Y, Bachoo R, Johnson JE, Zhang CL*. SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain. Stem Cell Reports. 2015 Apr 22. pii: S2213-6711(15)00100-9. doi: 10.1016/j.stemcr.2015.03.006. PMID: 25921813.

  4. Su Z, Niu W, Liu ML, Zou Y, and Zhang CL*. In vivo conversion of astrocytes to neurons in the injured adult spinal cord. Nat Commun. 2014; doi: 10.1038/ncomms4338. PMCID: PMC3966078. Highlighted in The Scientist Magazine, Neurology Today, The Medical News, etc; recognized as one of 2014ís Big Advances in Science by The Scientist Magazine.

  5. Niu W, Zang T, Zou Y, Fang S, Smith DK, Bachoo R, and Zhang CL*. In vivo reprogramming of astrocytes to neuroblasts in the adult brain. Nat Cell Biol. 2013 Oct;15(10):1164-75. doi: 10.1038/ncb2843. Epub 2013 Sep 22. PMCID: PMC3867822. Highlighted in Nature Reviews Neuroscience, F1000, The Scientist Magazine, etc.

  6. Liu ML, Zang T, Zou Y, Chang J, Gibson J, Huber KM, and Zhang CL*. Small molecules enable Neurogenin2 to efficiently convert human fibroblasts to cholinergic neurons. Nat Commun. 2013 4:2183 doi: 10.1038/ncomms3183. PMCID: PMC3843951. Highlighted in Neural Cell News 7.29.

  7. Qin S, Zou Y, and Zhang CL*. Crosstalk between KLF4 and STAT3 regulates axon regeneration. Nat Commun. 2013;4:2633. doi: 10.1038/ncomms3633. PMCID: PMC3867821.

  8. Zou Y, Niu W, Qin S, Downes M, Burns DK, and Zhang CL*. The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche. Mol Cell Biol. 2012 Dec;32(23):4811-20. doi: 10.1128/MCB.01122-12. Epub 2012 Oct 1. PMCID: PMC3497606. Highlighted in Neural Cell News 6.39.

  9. Qin S, Liu M, Niu W, Zhang CL*. Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21117-21. Epub 2011 Dec 12. PMCID: PMC3248552.

  10. Niu W, Zou Y, Shen C, and Zhang CL*. Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX. J Neurosci. 2011 Sep 28;31(39):13816-28. PMCID: PMC3192402.

  11. Mei J, Bachoo R, Zhang CL*. MicroRNA-146a Inhibits Glioma Development by Targeting Notch1. Mol Cell Biol. 2011 Sep;31(17):3584-92. Epub 2011 Jul 5. PMCID: PMC3165557. Top 5 of the most read articles in MCB in July.

  12. Zhang CL, Zou Y, He W, Gage FH, Evans RM. A role for adult TLX-positive neural stem cells in learning and behavior. Nature. 2008 Feb 21;451(7181):1004-7. Epub 2008 Jan 30. Featured Article in Nature Neuroscience Gateway. Science in the Spotlight in Alliance for Aging Research. Featured in Scientific American, Science Daily, etc.

  13. Zhang CL, Zou Y, Yu R, Gage FH, Evans RM. Nuclear Receptor TLX Prevents Retinal Dystrophy and Recruits the Corepressor Atrophin1. Genes and Development. 2006 May; 20(10):1308-20.

  14. Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell.2002 Aug 23;110(4):479-88. Featured in News and Views in Nature Medicine, The Dallas Morning News, etc.

  15. Zhang CL, McKinsey TA, Olson EN. Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol. 2002 Oct;22(20):7302-12.

  16. Zhang CL, McKinsey TA, Olson EN. The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. Proc Natl Acad Sci U S A. 2001, 98(13):7354-9.

  17. Zhang CL, McKinsey TA, Lu JR, Olson EN. Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. J Biol Chem. 2001 Jan 5;276(1):35-9.

Complete list of published work in MyBibliography