1. Bulut G.*, Sulahian R.*, Ma Y., Chi N. and Huang L.J. Ubiquitination regulates the internalization, endo-lysosomal sorting, and signaling of the erythropoietin receptor. Journal of Biological Chemistry 286(8): 6449-6457 (2011). (*equal first authorship)

  2. Wang H., Huang L.J., Liu Z., Garcia R., Li S. and Galliani C.A. Erythrosarcoma presents as bilateral ovarian masses in an infant with pure erythroid leukemia. Human Pathology Jan. 14 (2011).  

  3. Tirado C.A., Chen W., Huang L.J., Laborde C., Hiemenz M., Lou Z., Valdez F., Winick N., Patel S., Smart R. L., Garcia R., and Koduru P. Novel JAK2 rearrangement resulting from a t(9;22)(p24;p11.2) in B- acute lymphoblastic leukemia. Leukemia Research. 34(12):1674-1676 (2010).

  4. Patrick, D.M., Zhang C. C., Yao H., Qi X., Schwartz R.J., Huang L.J. and Olson E.N. microRNA-451 Regulates Erythroid Differentiation by Repressing 14-3-3-zeta. Genes and Development 24: 1620-1633 (2010).

  5. Huang L.J., Shen Y, and Bulut G. Advances in understanding the pathogenesis of primary familial and congenital polycythaemia. British Journal of Hematology. (accepted) (2010).

  6. Zhao L., Ma Y. Seemann J. and Huang L.J. A regulating role of JAK2 FERM domain in hyperactivation of JAK2(V617F). Biochemical Journal Nov. 24th (2009).

  7. Gao S., Wang Q., Huang L.J., Lum L. and Chen C. Chemical and Biological Studies of Nakiterpiosin and Nakiterpiosinone. Journal of the American Chemical Society (accepted) (2009).

  8. Huang L.J., Shen Y, and Bulut G. Advances in understanding the pathogenesis of primary familial and congenital polycythaemia. British Journal of Hematology. (accepted) (2010).

  9. Zhao L., Dong H., Zhang C.C., Kinch L., Osawa M., Iacovino M., Grishin N.V., Kyba M., and Huang L.J. A JAK2 inter-domain linker relays Epo receptor engagement signals to kinase activation. Journal of Biological Chemistry. July 28th (2009).

  10. Sulahian R, Cleaver O, Huang LJ. Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia. Blood. 113(21): 5287-97 (2009).

  11. Liu X, Huang LJ, and HF. Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F J Biol Chem. 2008 Feb 29;283(9):5258-66.

  12. Michaely P, Zhao Z, Li WP, Garuti R, Huang LJ, Hobbs HH, Cohen JC. Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR. EMBO J. 2007 Jul 25;26(14):3273-82.

  13. Tong W, Sulahian R, Gross AW, Hendon N, Lodish HF, Huang LJ. The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms. J Biol Chem. 2006 Dec 15;281(50):38930-40.

  14. Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, Ramya MA, Zhao Z, Chandrika KN, Padma N, Harsha HC, Yatish AJ, Kavitha MP, Menezes M, Choudhury DR, Suresh S, Ghosh N, Saravana R, Chandran S, Krishna S, Joy M, Anand SK, Madavan V, Joseph A, Wong GW, Schiemann WP, Constantinescu SN, Huang LJ, Khosravi-Far R, Steen H, Tewari M, Ghaffari S, Blobe GC, Dang CV, Garcia JG, Pevsner J, Jensen ON, Roepstorff P, Deshpande KS, Chinnaiyan AM, Hamosh A, Chakravarti A, Pandey A. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res. 2003 Oct;13(10):2363-71.

  15. Flint-Ashtamker G, Eisen-Lev R, Cohen J, Jun-shen, Huang LJ, Neumann D. Amino acid residues 268-276 of the erythropoietin receptor contain an endocytosis motif and are required for erythropoietin-mediated proliferation. FEBS Lett. 2002 May 8;518(1-3):189-94.

  16. Huang LJ, Constantinescu SN, Lodish HF. The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol Cell. 2001 Dec;8(6):1327-38.

  17. Perkins GA, Wang L, Huang LJ, Humphries K, Yao VJ, Martone M, Deerinck TJ, Barraclough DM, Violin JD, Smith D, Newton A, Scott JD, Taylor SS, Ellisman MH. PKA, PKC, and AKAP localization in and around the neuromuscular junction. BMC Neurosci. 2001;2:17.

  18. Rodriguez C, Huang LJ, Son JK, McKee A, Xiao Z, Lodish HF. Functional cloning of the proto-oncogene brain factor-1 (BF-1) as a Smad-binding antagonist of transforming growth factor-beta signaling. J Biol Chem. 2001 Aug 10;276(32):30224-30.

  19. Constantinescu SN*, Huang LJ*, Nam H, Lodish HF. The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif. Mol Cell. 2001 Feb;7(2):377-85. (*equal first authorship).

  20. Huang LJ, Wang L, Ma Y, Durick K, Perkins G, Deerinck TJ, Ellisman MH, Taylor SS. NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum. J Cell Biol. 1999 May 31;145(5):951-9.

  21. Harada H, Becknell B, Wilm M, Mann M, Huang LJ, Taylor SS, Scott JD, Korsmeyer SJ. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell. 1999 Apr;3(4):413-22.

  22. Banky P, Huang LJ, Taylor SS. Dimerization/docking domain of the type Ialpha regulatory subunit of cAMP-dependent protein kinase. Requirements for dimerization and docking are distinct but overlapping. J Biol Chem. 1998 Dec 25;273(52):35048-55.

  23. Huang LJ, Taylor SS. Dissecting cAMP binding domain A in the RIalpha subunit of cAMP-dependent protein kinase. Distinct subsites for recognition of cAMP and the catalytic subunit. J Biol Chem. 1998 Oct 9;273(41):26739-46.

  24. Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11184-9.

  25. Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. J Biol Chem. 1997 Mar 21;272(12):8057-64.