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- Seppen, J, Barry, SC, Klinkspoor, H, Katen LJ, Lee, SP, Garcia JV, and Osborne WRA. Lentiviral gene transfer into quiescent human and canine polarized intestinal epithelial cells. J. Virology 74, 7642-7645, 2000.
- Barry, SC, Seppen, J, Foster, JL, Ochs, H, Garcia JV, and Osborne, WRA. Lentiviral and murine retroviral transduction of T-cells for expression of human CD40 ligand. Human Gene Therapy 11, 223-232, 2000.
- Gatlin J, Douglas J, Evans JT, Collins RH, Wendel GD and Garcia JV. In vitro Selection of Lentivirus Vector Transduced Human CD34+ Cells. Human Gene Therapy 11,1949-1957, 2000.
- Evans JT, Okamoto Y, Douek D, McFarland R, Gatlin J, Koup RA and Garcia JV. Thymocyte differentiation from Lentivirus-Marked CD34+ Cells in Infant and Adult Human Thymus. J. Immunological Methods 245, 31-43, 2000.
- Evans JT and Garcia JV. Lentivirus Vector Mobilization and Spread by the Human Immunodeficiency Virus. Human Gene Therapy 11, 2331-2339, 2000.
- Arora VA, Molina RP, Foster JL, Blakemore JL, Chernoff J, Fredericksen BL and Garcia JV. Lentiviral Nef Specifically Activates Pak2. J. Virology 74, 11081-11087, 2000.
- Evans JT, Cravens P, Lipsky PE and Garcia JV. Differentiation and Expansion of Lentivirus-Vector Marked Dendritic Cells Derived from Human CD34+ Cells. Human Gene Therapy 11, 2483-2492, 2000.
- Foster JF, Molina RP, Luo T, Arora VK, Huang Y, Ho D. and Garcia JV. Genetic and Functional Diversity Amongst HIV-1 Subtype B Nef Primary Isolates. J. Virology 75, 1672-1680, 2001.
- Luo T, Fredericksen BL, Hasumi K, Endo A, and Garcia JV. Human immunodeficiency Virus Type-1 Nef-Induced CD4 Cell Surface Downregulation Is inhibited By a Novel Antibiotic. J. Virology 75, 2488-2492, 2001.
- Gatlin J, Padgett A, Melkus MW, Kelly PF and Garcia JV. Long-Term Engraftment of NOD/SCID Mice with Human CD34+ Cells Transduced by a Self-Inactivating (SIN) HIV-1 Vector. Human Gene Therapy 12, 1079-1089, 2001.
- Gatlin J, Unett DJ, Lerner MR, and Garcia JV. Efficient long-term transgene expression in Xenopus laevis dermal melanopores. Pigment Cell Research 14, 275-282, 2001.
- Gatlin J, Melkus MW, Padgett A, Kelly PF and Garcia JV. Engraftment of NOD/SCID mice with human CD34+ cells transduced by concentrated oncoretroviral vector particles pseudotyped with the feline endogenous virus (RD114) envelope glycoprotein. J. Virology 75, 9995-9999, 2001.
- Krynetskaia NF, Feng JY, Krynetski EY, Garcia JV, Anderson KS and Evans WE. DNA Incorporation of Mercaptopurine’s Active Metabolite, Deoxythioguanosine Triphosphate, Impairs HIV Replication. FASEB Journal 15, 1902-1908, 2001.
- Musk P, Szamania S, Galloway A, Johnson K, Scott A, Ta N, Guttman S, Bridges K, Bruorton M, Gatlin J, Garcia JV, Lamb L, Chian KY, Spencer T, Henslee-Downey J and Rhee FV. EBV-specific cytotoxic T cells for prevention of EBV-induced lymphoma in haplo-identical allogeneic stem cell transplantation. J. Immunotherapy 24, 312-322, 2001.
- Evans JT, Cravens P, Gatlin J, Kelly P, Lipsky PE and Garcia JV. Pre-Clinical Evaluation of an In Vitro Selection Protocol for the Enrichment of Transduced CD34+ Cell Derived Human Dendritic Cells. Gene Therapy 8, 1427-1435, 2001.
- Arora VA, Fredericksen BL and Garcia JV. Nef: agent of cell subversion. Microbes and Immunity 4,189-199, 2002.
- Fredericksen BL, Yao J, Luo T and Garcia JV. Inhibition of Endosomal/Lysosomal Degradation Increases the Infectivity of the Human Immunodeficiency Virus. J. Virology. 76, 11440-11446, 2002.
- Wilund KR, Yi M, Campagna F, Arca M, Zuliani G, Fellin R, Ho YK, Garcia JV, Hobbs HH, Cohen JC. Molecular Mechanisms of Autosomal Recessive Hypercholesterolemia. Human Mol. Genetics. 11, 3019-30, 2002.
- Hamra FK, Gatlin JE, Chapman KM, Grellhesl DM, Garcia JV, Hammer RE and Garbers DL. Production of Transgenic Rats by Direct Germline Transmission. Proc. Nat. Acad. Sci. USA. 99, 14931-14936, 2002
- Wei B, Arora VK, Foster JL, Sodora DL and Garcia JV. In Vivo Analysis of Nef Function. Current HIV Research. Current HIV Res. 1:41-50, 2003.
- Gatlin J, Islas-Ohlmayer M and Garcia JV. Detection and Titration of Lentivirus Vectors. Meth. Mol. Biol. 229:57-68, 2003.
- Gatlin J, Melkus MW, Padgett A, Petroll WM, Cavanaugh D, Garcia JV and Jester JV. In Vivo Fluorescent Labeling of Corneal Wound Healing Fibroblasts. Exp. Eye Res. 76, 361-371, 2003.
- Palucka AK, Gatlin JE, Blanck JP, Melkus MW, Clayton S, Ueno H, Kraus ET, Cravens P, Bennett L, Padgett-Thomas A, Marches F, Islas-Ohlmayer M, Garcia JV and Banchereau J. Human Dendritic Cell Subsets in NOD/SCID Mice Engrafted with CD34+ Hematopoietic Progenitors. Blood. 102, 3302- 3310, 2003.
- Jester JV, Ward B, Takashima A, Gatlin J, Garcia JV, Cavanagh HD, and Petroll WM. 4-Dimensional Multiphoton Confocal Microscopy: The New Frontier in Cellular Imaging. The Ocular Surface. 4, 10-20, 2004.
- Islas-Ohlmayer M, Padgett-Thomas A, Domiati-Saad R, Melkus MW, Cravens PD, Martin M del P, Netto G, and Garcia JV. Experimental Infection of NOD/SCID Mice Reconstituted with Human CD34+ Cells with Epstein-Barr Virus. J. Virol. 78, 13891-13900, 2004.
- Cravens PD, Melkus MW, Padgett-Thomas A, Islas-Ohlmayer M, Martin MP and Garcia JV. In vivo modeling of human dendritic cell development, differentiation and function: phenotypic and functional analysis during the steady state and acute response to endotoxin. Stem Cells. 23, 264-278 (2005).
- Binck BW, Tsen MF, Islas M, White JD, Schultz RA, Willis MS, Garcia JV, Horton JW, Thomas JA. Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock. Am. J. Phys. Heart. 288, 577-583 (2005).
- Wei B, Denton P, Luo T, Foster JL, and Garcia JV. Inactivation of Human Immunodeficiency Virus Type 1 by Proteasomes and Lysosomes. J. Virology. 79, 5705-5712 (2005)
- Raney A, Kuo LS, Baugh LL, Foster JL and Garcia JV. Reconstitution and molecular analysis of an active Nef/PAK-2 complex. J. Virology. 79, 12732-12741 (2005).
- Bente DA, Melkus MW, Garcia JV and Rico-Hesse, R. Dengue fever in humanized NOD/SCID mice. J. Virology. 79, 13797-13799 (2005).
- Wei B, Arora VK, Raney A, Kuo L, Xiao G-H, O’Neill E, Testa JR, Foster JL and Garcia JV. Activation of p21-activated kinase by human immunodeficiency virus type-1 Nef induces merlin phosphorylation. J. Virology. 79, 14976-14980 (2005).
- O’Neill E, Kuo LS, Krisko JF, Tomchick DR, Garcia JV, and FosterJL. Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef. J. Virology 80, 1311-1320 (2006).
- Agopian J, Wei BL, Garcia JV, and Gabuzda D. A Hydrophobic Binding Surface on the Human Immunodeficiency Virus Type 1 Nef Core Is Critical for Association with p21-Activated Kinase 2. J. Virology 80, 3050-3061 (2006).
- Foster, JL and Garcia JV. HIV Pathogenesis: Nef loses control. Cell 125, 1034-1035 (2006).
- O'Neill E, Baugh LL, Novitsky VA, Essex ME and Garcia JV. Itra- and intersubtype alternative Pak2-activating structural motifs of HIV-1 Nef. J. Virology. 80, 8824-8829 (2006)
- Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, Othieno F, Wege AK, Hasse AT, and Garcia JV. Humanized mice mount specific adaptive and innate immune response to EBV and TSST-1. Nature Medicine. 12, 1322-1326 (2006)
- Agopian K, Wei BL, Garcia JV and Gabuzda D. CD4 and MHC-I Downregulation are Conserved in Primary HIV-1 Nef Alleles from Brain and Lymphoid Tissues, but Pak2 Activation is Highly Variable. Virology. 358, 119-135 (2007).
- Sun Z, Denton PW, Estes JD, Othieno F, Wei B, Wege AK, Melkus MW, Padgett-Thomas A, Zupancic M, Haase AT and Garcia JV. Intrarectal transmission, systemic infection and CD4 T cell depletion in humanized mice infected with HIV-1. J. Exp. Med. 204, 705-714 (2007).
- Raney A, Shaw AY, Foster JL and Garcia JV. Structural constraints on human immunodeficiency virus type 1 Nef function. Virology 368, 7-16 (2007).
- Denton PW, Estes JD, Sun Z, Othieno F, Wei B, Wege AK, Powell DA, Payne D, Haase AT and Garcia JV. Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice. PLoS Medicine Vol. 5, No. 1, e16 doi:10.1371 (2008).
- Wege A, Denton PD, Estes JD and Garcia JV. Functional and phenotypic characterization of the humanized BLT mouse model. In Press (Current Topics in Microbiology and Immunology).
- Wang J, Shackelford JM, Selliah N, Shivers DK, O’Neill E, Garcia JV, Karuppiah M, Weiner D, Yu X-F, Gabuzda D and.Finkel TH. The HIV-1 Vif Protein Mediates Ubiquitination of Vpr, Reducing Intracellular Expression and Vpr-Induced Cell Cycle Arrest. In Press (DNA and Cell Biology).
- Buzina A, Lo M, Moffett A, Hotta A, Fussner E, Bharadwaj R, Pasceri P, Garcia JV, Bazett-Jones D, and Ellis J. b-globin LCR and intron elements cooperate and direct spatial reorganization for gene therapy. In press (PLoS Genetics).
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