| Our lab studies pediatric urological diseases and defects, ranging from VACTERL association, hypospadias, cryptorchidism, kidney stones, and testicular torsion. Our long-term goal is to understand the embryonic and molecular basis of these rare and common birth defects and disorders. The laboratory currently utilizes genetically engineered mouse models of pediatric urologic birth defects to further study these disorders. For translational research, Dr. Baker has built a large and valuable human DNA and tissue repository from common and rare pediatric genitourinary birth defects and disorders. We hope to use this database as a foundation for understanding how disruptions in a specific patient’s gene expression can cause a certain urological disorder. |
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Testis Spermatogenesis - Mouse Age P 24
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Ephrin-B2 Cloaca Immunofluorescence |
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| GFP Mouse | Testicular Torsion |