RELEVANT PUBLICATIONS

Tolson KP, Gemelli T, Gautron L, Elmquist JK, Zinn AR* and Kublaoui BM*. (*Equal contributors.) 2010. Postnatal Sim1 deficiency causes hyperphagic obesity and reduced Mc4r and Oxytocin expression. J. Neurosci 30:3803.

Kublaoui BM, Gemelli T, Tolson KP, Wang Y, Zinn AR. 2008. Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice. Mol Endocrinol 22:.1723-1734. PMCID: 2453606

Kublaoui BM, Holder JL Jr, Gemelli T, Zinn AR. 2006. Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons. Mol Endocrinol 20:2483-2492.

Kublaoui BM, Holder JL Jr, Tolson KP, Gemelli T, Zinn AR. 2006. SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake. Endocrinology 147:4542-4549.

Holder Jr JL, Zhang L, Kublaoui BM, DiLeone RJ, Oz OK, Bair CH, Lee YH, and Zinn AR. 2004. Sim1 gene dosage modulates the homeostatic feeding response to increased dietary fat in mice. Am J Physiol Endocrinol Metab 287, E105-13.

Holder JL, Butte NF, and Zinn AR  2000. Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Hum Mol Gen 9:101-8.

Garcia