| Risk
Category |
LDL-Cholesterol
Goal |
LDL
Level at which to Initiate Therapeutic Lifestyle Changes (TLC) |
When
to begin Medications |
|
High Risk:
CHD or CHD Risk Equivalents (10-year risk > 20%)
|
< 100 mg/dL
(optional goal: <70 mg/dL)
|
≥
100 mg./dL |
≥
100 mg/dL
(< 100 mg/dL: consider drug options) |
|
Moderately High Risk:
2+ Risk Factors (10-year risk 10%-20%) |
< 130 mg/dL |
≥ 130 mg/dL |
≥ 130 mg/dL
(100-129 mg/dL, consider drug options) |
|
Moderate Risk:
2+ Risk Factors (10-year risk <10%) |
< 130 mg/dL |
≥ 130 mg/dL |
≥ 160 mg/dL |
Lower Risk:
0-1 Risk Factor |
< 160 mg/dL |
≥ 160 mg/dL |
≥ 190 mg/dL
(160-190 mg/dL; LDL-lowering drug optional |
| Source:
Adapted from Grundy SM et al. Implications of recent clinical
trials for the National Cholesterol Education Program Adult
Treatment Panel III Guidelines. Circulation. 2004;110:227-239. |