Dr. Herz was born in Bad
a small town in Southern Germany. He studied
at the University
from 1977-1983, where he also completed
his work on his doctoral thesis in Pharmacology with Prof.
After graduating from Medical School in
1983 he practiced medicine as a surgical resident in Germany
and England. In 1985, Dr. Herz joined the laboratory of Dr.
Keith Stanley at the European Molecular Biology Laboratory
Heidelberg where he discovered a novel member of the LDL receptor
gene family, the LDL receptor-related protein (LRP). In order
to continue his studies on the role of LRP in cholesterol
metabolism, in particular to investigate a hypothesized role
of this gargantuan cell surface receptor in the transport
of dietary lipids from the gut to the liver, he joined the
laboratory of Drs. Michael Brown and Joseph Goldstein in 1989. In subsequent research, Dr. Herz proved that LRP
functions in the transport of dietary lipids. He
identified the first mechanisms by which lipoprotein receptors engage in
cellular signaling in neurons and in smooth muscle of the vasculature and
showed that these signaling pathways are essential for the development of
the brain, synaptic function and maintenance of vascular wall integrity.
In 1991, Dr.Herz joined the faculty of the Department of Molecular
Genetics as an Assistant Professor. He was promoted to Associate
Professor in 1995 and to the rank of Professor in 1998. He
has received fellowships from the Boehringer
and the European Molecular Biology
Laboratory. In 1991, he was selected as a Syntex Scholar and
for a Lucille P. Markey Scholar Award. He became an Established
Investigator of the American Heart Association in 1996. In
2001, Dr. Herz was honored with the prestigious Wolfgang Paul
Award of the Humboldt Society of Germany and the Ministry of Education of Germany. He became
the Thomas O. and Cinda Hicks Family Distinguished Chair in Alzheimer's
Disease Research in 2002 and received the Heinrich-Wieland Prize for Excellence in Lipid Research in 2007.