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Lukowski, R., Weinmeister, P., Bernhard, D., Feil, S., Gotthardt, M., Herz, J., Massberg, S., Zernecke, A., Weber, C., Hofmann, F., and Feil R. (2008) Role of Smooth Muscle cGMP/cGKI Signaling in Murine Vascular Restenosis. Arterioscler Thromb Vasc Biol., 28: 1244-1250.
Larouche, M., Beffert, U., Herz, J., Hawkes, R. (2008) The reelin receptors apoer2 and vldlr coordinate the patterning of purkinje cell topography in the developing mouse cerebellum. PLoS ONE 3, e1653.
Akopians, A.L., Babayan, A.H., Beffert, U., Herz, J., Basbaum, A.I., Phelps, P.E. (2008) Contribution of the Reelin signaling pathways to nociceptive processing. Eur J Neurosci. 27, 523-37.
Hofmann, S.M., Zhou, L., Perez-Tilve, D., Greer, T., Grant, E., Wancata, L., Thomas, A., Pfluger, P.T., Basford, J.E., Gilham, D., Herz, J., Tschöp, M.H., Hui, D.Y. (2007) Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J. Clin. Invest. 117, 3271-82.
Liu, Q., Zerbinatti, C.V., Zhang, J., Hoe, H.S., Wang, B., Cole, S.L., Herz, J., Muglia, L., Bu, G. (2007) Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 56, 66-78.
Boucher, P., Li, W.P., Matz, R.L., Takayama, Y., Auwerx, J., Anderson, R.G., Herz, J. (2007) LRP1 Functions as an Atheroprotective Integrator of TGFbeta and PDFG Signals in the Vascular Wall: Implications for Marfan Syndrome. PLoS ONE 2, e448.
Zhang, G., Assadi, A.H., McNeil, R.S., Beffert, U., Wynshaw-Boris, A., Herz, J., Clark, G.D., D'Arcangelo, G. (2007) The Pafah1b Complex Interacts with the Reelin Receptor VLDLR. PLoS ONE 2, e252.
Herz, J. (2007) Overview: the long and winding road to understanding Alzheimer's disease. Neuron 53, 477-479.
Jones, C., Garuti, R., Michaely, P., Li, W.P., Maeda, N., Cohen, J.C., Herz, J., Hobbs, H.H. (2007) Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J. Clin. Invest. 117, 165-174.
Beffert, U., Nematollah Farsian, F., Masiulis, I., Hammer, R.E., Yoon, S.O., Giehl, K.M., Herz, J. (2006) ApoE receptor 2 controls neuronal survival in the adult brain. Curr. Biol. 16, 2446-2452.
Herz, J., Chen, Y. (2006) Reelin, lipoprotein receptors and synaptic plasticity. Nat. Rev. Neurosci. 7, 850-859.
Hu, L., Boesten, L.S., May, P., Herz, J., Bovenschen, N., Huisman, M.V., Berbee, J.F., Havekes, L.M. , van Vlijmen, B.J. Tamsma, J.T. (2006) Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice. Arterioscler. Thromb. Vasc. Biol. 26, 2710-2715.
Johnson, E.B., Steffen, D.J., Lynch, K.W., Herz, J. (2006) Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease. Genomics. 88, 600-609.
Herz, J. (2006) The switch on the RAPper's necklace... Mol. Cell 23, 451-455.
Li, X., Herz, J., Monard, D. (2006) Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1. J. Cell. Biochem. 99, 936-951.
Cao, C., Lawrence, D.A., Li, Y., Von Arnim, C.A., Herz, J., Su, E.J., Makarova, A., Hyman, B.T., Strickland, D.K., Zhang, L. (2006) Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J. 25, 1860-1870.
Beffert, U., Durudas, A., Weeber, E.J., Stolt, P.C., Giehl, K.M., Sweatt, J.D., Hammer, R.E., Herz, J. (2006) Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity.
J. Neurosci. 26, 2041-2052.
Guenette, S., Chang, Y., Hiesberger, T., Richardson, J.A., Eckman, C.B., Eckman, E.A., Hammer, R.E., Herz, J. (2006) Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 25, 420-431.
Johnson, E.B., Hammer, R.E., Herz, J. (2005) Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum. Mol. Genet. 14, 3523-3538.
Garuti, R., Jones, C., Li, W.P., Michaely, P., Herz, J., Gerard, R.D., Cohen, J.C., Hobbs, H.H. (2005) The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits. J. Biol. Chem. 280, 40996-41004.
May, P., Herz, J., Bock, H.H. (2005) Molecular mechanisms of lipoprotein receptor signalling. Cell Mol. Life Sci. 62, 2325-2338.
Uwe Beffert, Edwin Weeber, Gerardo Morfini, Jane Ko, Scott T. Brady, Li-Huei Tsai, J. David Sweatt, and Joachim Herz (2004) Reelin and Cdk5 dependent signals cooperate in regulating neuronal migration and synaptic transmission. J. Neuroscience 24, 1897-1906.
Hans H. Bock and Joachim Herz (2003) Reelin Activates Src Family Tyrosine Kinases in Neurons. Current Biology 13, 18-26
Jochen Brich, Feng-Shiun Shie, Brian W. Howell, Renhua Li, Katalin Tus, Edward K. Wakeland, Lee-Way Jin, Marc Mumby, Gary Churchill, Joachim Herz, and Jonathan A. Cooper (2003) Genetic modulation of tau phosphorylation in the mouse. J. Neuroscience 23, 187-192
Philippe Boucher, Pingsheng Liu, Michael Gotthardt, Thomas Hiesberger, Richard G. W. Anderson, and Joachim Herz (2002) PDGF mediates tyrosine phosphorylation of the cytoplasmic domain of the LDL receptor-related protein (LRP) in caveolae. J. Biol. Chem., 277, 15507-13
Joachim Herz and Hans. H. Bock (2002) Lipoprotein Receptors in the Nervous System. Ann. Rev. Biochem. 71, 405-34
SIGNIFICANT PUBLICATIONS
Marion Trommsdorff, Michael Gotthardt, Thomas Hiesberger, John Shelton, Walter Stockinger, Johannes Nimpf, Robert E. Hammer, James A. Richardson, and Joachim Herz (1999) Reeler/Disabled-Like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL receptor and ApoE receptor-2. Cell 97, 689-701
Thomas Hiesberger, Marion Trommsdorff, Brian W. Howell, Andre Goffinet, Marc C. Mumby, Jonathan A. Cooper, and Joachim Herz (1999) Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of the adaptor protein Disabled-1 and modulates tau phosphorylation. Neuron 24, 481-489
Thomas E. Willnow, Zeqi Sheng, Shun Ishibashi, and Joachim Herz (1994) Inhibition of Hepatic Chylomicron Remnant Uptake by Gene Transfer of A Receptor Antagonist. Science 264, 1471-1474
Joachim Herz, Ute Hamann, Sissel Rogne, Ola Myklebost, Heinrich Gausepohl, and Keith K. Stanley (1988) Surface location and high affinity for calcium of a 500 kd liver membrane protein closely related to the LDL receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7, 4119-4127
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