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 Lukowski, R., Weinmeister, P., Bernhard, D., Feil, S., Gotthardt, M., Herz, J., Massberg, S., Zernecke, A., Weber, C., Hofmann, F., and Feil R. (2008)
Role of Smooth Muscle cGMP/cGKI Signaling in Murine Vascular Restenosis.
Arterioscler Thromb Vasc Biol., 28: 1244-1250.
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 Larouche, M., Beffert, U., Herz, J., Hawkes, R. (2008)
The reelin receptors apoer2 and vldlr coordinate the patterning of purkinje cell topography in the developing mouse cerebellum.
PLoS ONE 3, e1653.
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Akopians, A.L., Babayan, A.H., Beffert, U., Herz, J., Basbaum, A.I., Phelps, P.E. (2008)
Contribution of the Reelin signaling pathways to nociceptive processing.
Eur J Neurosci. 27, 523-37. |
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Hofmann, S.M., Zhou, L., Perez-Tilve, D., Greer, T., Grant, E., Wancata, L., Thomas, A., Pfluger, P.T., Basford, J.E., Gilham, D., Herz, J., Tschöp, M.H., Hui, D.Y. (2007)
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice.
J. Clin. Invest. 117, 3271-82. |
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Liu, Q., Zerbinatti, C.V., Zhang, J., Hoe, H.S., Wang, B., Cole, S.L., Herz, J., Muglia, L., Bu, G. (2007)
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.
Neuron 56, 66-78. |
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Boucher, P., Li, W.P., Matz, R.L., Takayama, Y., Auwerx, J., Anderson, R.G., Herz, J. (2007)
LRP1 Functions as an Atheroprotective Integrator of TGFbeta and PDFG Signals in the Vascular Wall: Implications for Marfan Syndrome.
PLoS ONE 2, e448. |
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Zhang, G., Assadi, A.H., McNeil, R.S., Beffert, U., Wynshaw-Boris, A., Herz, J., Clark, G.D., D'Arcangelo, G. (2007)
The Pafah1b Complex Interacts with the Reelin Receptor VLDLR.
PLoS ONE 2, e252. |
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Herz, J. (2007)
Overview: the long and winding road to understanding Alzheimer's disease.
Neuron 53, 477-479. |
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Jones, C., Garuti, R., Michaely, P., Li, W.P., Maeda, N., Cohen, J.C., Herz, J., Hobbs, H.H. (2007)
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia.
J. Clin. Invest. 117, 165-174. |
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Beffert, U., Nematollah Farsian, F., Masiulis, I., Hammer, R.E., Yoon, S.O., Giehl, K.M., Herz, J. (2006)
ApoE receptor 2 controls neuronal survival in the adult brain.
Curr. Biol. 16, 2446-2452. |
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Herz, J., Chen, Y. (2006) Reelin, lipoprotein receptors and synaptic plasticity.
Nat. Rev. Neurosci. 7, 850-859. |
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Hu, L., Boesten, L.S., May, P., Herz, J., Bovenschen, N., Huisman, M.V.,
Berbee, J.F., Havekes, L.M. , van Vlijmen, B.J. Tamsma, J.T. (2006) Macrophage low-density lipoprotein
receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice.
Arterioscler. Thromb. Vasc. Biol. 26, 2710-2715. |
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Johnson, E.B., Steffen, D.J., Lynch, K.W., Herz, J. (2006)
Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in
autosomal recessive mulefoot disease. Genomics. 88, 600-609. |
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Herz, J. (2006) The switch on the
RAPper's necklace... Mol. Cell 23, 451-455. |
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Li, X., Herz, J., Monard, D. (2006) Activation of ERK signaling
upon alternative protease nexin-1 internalization mediated by syndecan-1. J. Cell. Biochem. 99, 936-951. |
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Cao, C., Lawrence, D.A., Li, Y., Von Arnim, C.A., Herz, J., Su,
E.J., Makarova, A., Hyman, B.T., Strickland, D.K., Zhang, L. (2006) Endocytic receptor LRP
together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J. 25, 1860-1870. |
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Beffert, U., Durudas, A., Weeber, E.J., Stolt, P.C., Giehl,
K.M., Sweatt, J.D., Hammer, R.E., Herz, J. (2006) Functional dissection of Reelin signaling by site-directed disruption of
Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in
development and synaptic plasticity.
J. Neurosci. 26, 2041-2052. |
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Guenette, S., Chang, Y., Hiesberger, T., Richardson, J.A., Eckman,
C.B., Eckman, E.A., Hammer, R.E., Herz, J. (2006) Essential roles for the FE65 amyloid precursor
protein-interacting proteins in brain development. EMBO J. 25, 420-431. |
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Johnson, E.B., Hammer, R.E., Herz, J. (2005) Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum. Mol. Genet. 14, 3523-3538. |
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Garuti, R., Jones, C., Li, W.P., Michaely, P., Herz, J., Gerard, R.D., Cohen, J.C., Hobbs, H.H. (2005) The modular adaptor protein autosomal recessive hypercholesterolemia (ARH)
promotes low density lipoprotein receptor clustering into clathrin-coated pits. J. Biol. Chem. 280, 40996-41004. |
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May, P., Herz, J., Bock, H.H. (2005) Molecular mechanisms of lipoprotein receptor signalling. Cell Mol. Life Sci. 62, 2325-2338. |
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Uwe Beffert, Edwin Weeber, Gerardo
Morfini, Jane Ko, Scott T. Brady, Li-Huei Tsai, J. David Sweatt,
and Joachim Herz (2004) Reelin and Cdk5 dependent signals
cooperate in regulating neuronal migration and synaptic transmission.
J. Neuroscience 24, 1897-1906. |
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Hans H. Bock and Joachim Herz (2003)
Reelin Activates Src Family Tyrosine Kinases in Neurons. Current
Biology 13, 18-26 |
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Jochen Brich, Feng-Shiun Shie, Brian
W. Howell, Renhua Li, Katalin Tus, Edward K. Wakeland, Lee-Way
Jin, Marc Mumby, Gary Churchill, Joachim Herz, and Jonathan
A. Cooper (2003) Genetic modulation of tau phosphorylation
in the mouse. J. Neuroscience 23, 187-192
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Philippe Boucher, Pingsheng Liu,
Michael Gotthardt, Thomas Hiesberger, Richard G. W. Anderson,
and Joachim Herz (2002) PDGF mediates tyrosine phosphorylation
of the cytoplasmic domain of the LDL receptor-related protein
(LRP) in caveolae. J. Biol. Chem., 277, 15507-13 |
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Joachim Herz and Hans. H. Bock (2002)
Lipoprotein Receptors in the Nervous System. Ann. Rev. Biochem.
71, 405-34
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SIGNIFICANT PUBLICATIONS
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Marion Trommsdorff, Michael Gotthardt,
Thomas Hiesberger, John Shelton, Walter Stockinger, Johannes
Nimpf, Robert E. Hammer, James A. Richardson, and Joachim
Herz (1999) Reeler/Disabled-Like Disruption of Neuronal Migration
in Knockout Mice Lacking the VLDL receptor and ApoE receptor-2.
Cell 97, 689-701 |
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Thomas Hiesberger, Marion Trommsdorff,
Brian W. Howell, Andre Goffinet, Marc C. Mumby, Jonathan A.
Cooper, and Joachim Herz (1999) Direct binding of Reelin to
VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation
of the adaptor protein Disabled-1 and modulates tau phosphorylation.
Neuron 24, 481-489
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Thomas E. Willnow, Zeqi Sheng, Shun
Ishibashi, and Joachim Herz (1994) Inhibition of Hepatic Chylomicron
Remnant Uptake by Gene Transfer of A Receptor Antagonist.
Science 264, 1471-1474 |
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Joachim Herz, Ute Hamann, Sissel Rogne,
Ola Myklebost, Heinrich Gausepohl, and Keith K. Stanley (1988)
Surface location and high affinity for calcium of a 500 kd
liver membrane protein closely related to the LDL receptor
suggest a physiological role as lipoprotein receptor. EMBO
J. 7, 4119-4127
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