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Ye, J. "Hepatitis C virus: a new class of virus associated with particles derived from very low-density lipoproteins." Arterioscler. Thromb. Vasc. Biol. 32: 1099-103. (2012) |
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Denard, B., Seemann, J., Chen, Q., Gay, A., Huang, H., Chen, Y., Ye, J. "The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells." Cell Host Microbe 10: 65-74, (2011). |
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Ye, J. "Cell biology. Protease sets site-1 on lysosomes." Science 333: 50-51, (2011). |
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Ye, J., DeBose-Boyd, R.A. "Regulation of cholesterol and fatty acid synthesis." Cold Spring Harb. Perspect. Biol. 3: a004754. (2011) |
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Lee, J.N., Kim, H., Yao, H., Chen, Y., Weng, K., Ye, J. "Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis." Proc Natl Acad Sci U S A. 107: 21424-21429, (2010). |
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Brown, M.S., Ye, J., Goldstein, J.L. "HDL miR-ed down by SREBP introns." Science 328: 1495-1496, (2010). |
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Ikeda, Y., Demartino, G.N., Brown, M.S., Lee, J.N., Goldstein, J.L., Ye, J. "Regulated erad of a polytopic protein: p97 recruits proteasomes to
insig-1 before extraction from membranes." J. Biol. Chem. 284: 34889-34900, (2009). |
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Owen, D.M., Huang, H., Ye, J., Gale, M. Jr. "Apolipoprotein E on hepatitis C virion facilitates infection through
interaction with low-density lipoprotein receptor." Virology. 394: 99-108, (2009). |
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Lee, J.N., Zhang, X., Feramisco, J.D., Gong, Y., Ye, J. "Unsaturated fatty acids inhibit proteasomal degradation of insig-1 at a post-ubiquitination step." J. Biol. Chem. 283: 33772-33783 (2008). |
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Yao, H. and Ye,
J. "Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells." J. Biol. Chem. 283: 849-854 (2008). |
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Huang, H., Chen,
Y., and Ye, J.
"Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin E." Proc. Natl. Acad. Sci. USA 104: 18666-18670 (2007). |
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Ye,
J. "Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus." PLoS Pathog. 3: 1017-1022 (2007). |
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Huang, H., Sun, F., Owen, D.M., Li, W., Chen,
Y., Gale, M., Jr. and Ye, J.
"Hepatitis C Virus production by human hepatocytes dependent on assembly and
secretion of Very Low Density Lipoproteins." Proc. Natl. Acad. Sci. USA 104: 5848-5853 (2007). |
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Lee, J., Song, B., Debose-Boyd, R., and Ye,
J. "Sterol-regulated degradation of Insig-1 mediated by the membrane-bound
ubiquitin ligase gp78." J. Biol. Chem. 281: 39308-39315 (2006). |
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Gong, Y., Lee, J., Brown, M.S., Goldstein,
J.L., and Ye, J.
"Juxtamembranous aspartic acid in Insig-1 and Insig-2 is
required for cholesterol homeostasis." Proc. Natl. Acad.
Sci. USA 103: 6154-6159 (2006). |
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Lee, J., Gong, Y., Zhang, X., and Ye, J. "Proteasomal
degradation of ubiquitinated Insig proteins is determined by serine residues flanking
ubiquitinated lysines." Proc. Natl. Acad. Sci. USA 103: 4958-4963 (2006). |
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Gong, Y., Lee, J., Lee, P., Goldstein, J.L., Brown, M.S. and Ye, J.
"Sterol-regulated ubiquitination and degradation of Insig-1 creates a
convergent mechanism for feed back control of cholesterol synthesis and uptake."
Cell Metabolism 3: 15-24(2006). |
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Wang C., Hua, H., Gale, M., Brown,
M.S., Goldstein, J.L., and Ye, J. “Identification of
FBL2 as a geranylgeranylated cellular protein required for
hepatitis C virus RNA replication” Mol. Cell 18: 425-434 (2005). |
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Lee, J. and Ye, J. “Proteolytic activation of sterol
regulatory element-binding protein induced by cellular stress
through depletion of Insig-1” J. Biol. Chem.
279: 45257-45265 (2004). |
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Ye, J., Wang, C., Sumpter, R., Brown, M.S., Goldstein,
J.L., and Gale, M. “Disruption of hepatitis C virus
RNA replication through inhibition of host protein geranylgeranylation”
Proc. Natl. Acad. Sci. USA 100: 15865-15870 (2003).
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