Emerging Techniques in Keratoplasty


The start of the new millennium marked a paradigm shift in the field of corneal transplantation. There has been a trend away from full-thickness penetrating keratoplasty to lamellar keratoplasty procedures that allow for selective removal and replacement of the diseased corneal sub-layer.  Lamellar keratoplasty procedures are less-invasive, better preserve the structural integrity of the globe, and offer more rapid visual recovery for patients than traditional penetrating keratoplasty. 

Our research has focused on the outcomes of lamellar keratoplasty using the Department of Ophthalmology’s advanced anterior segment imaging capabilities, including confocal microscopy, anterior segment optical coherence tomography, and Scheimpflug photography.

Anterior Segment OCT after DSAEK

Legend: Rotating Scheimpflug imaging system (Pentacam) maps of corneal higher order aberrations (HOAs) of the central 6 mm (A) in a control eye (left: anterior corneal HOAs, right: posterior corneal HOAs), (B) in an eye that underwent penetrating keratoplasty (PKP), and in (C, D) 3 eyes that underwent Descemet stripping automated endothelial keratoplasy (DSAEK).



Click the play button below to watch a video describing DSEK

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