Subunits of protein phosphatase 2A

This table is a consensus list of the subunits of mammalian protein phosphatase 2A. Entries are limited to those proteins that have been shown to interact with PP2A catalytic subunits in biochemical experiments and in intact cells. With the exception of the alpha4 protein, which interacts directly with the catalytic subunit, the regulatory subunits bind to the core dimer of PP2A composed of a complex between a catalytic and scafflod (A) subunit. In addition to the proteins listed here, many other proteins have been shown to interact with PP2A. The genes and splice variants listed here predict that PP2A could theoretically assemble into 188 distinct oligomeric forms.