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Philip Boyer, MD, PhD

Education and Qualifications:
Undergraduate:
     Michigan State University
Graduate:
     Michigan State University
Medical School:
     MD, Michigan State University
Residency:
     Michigan State University, Anatomic and Clinical Pathology
Fellowship:
     Massachusetts General Hospital
     Neuropathology

Research Interests:
Iron metabolism in normal and diseased central nervous system
Neurodegenerative disease (Alzhimer disease, Parkinson disease
   
(Lewy body diseae), Amyotrophic Lateral Sclerosis
Muscle and nerve pathology
Tumors of the central and peripheral nervous systems

Professional Organizations:
College of American Pathologists
American Association of Neuropathologists
Society for Neuroscience
United States and Canadian Academy of Pathology
Association for Pathology Informatics

Selected Recent Publications and Presentations
Textbook Chapters:
Boyer PJ, Simmons Z, Nifong TP. Cerebrospinal fluid. In Lewandrowski K, ed. Clinical Chemistry: Laboratory Management and Clinical Correlations. Lippincott Williams & Wilkins, New York. 2002

McKeever PE, Boyer PJ. The Brain, Spinal Cord, and Meninges. In Diagnostic Surgical Pathology. 4th ed., Sternberg SS ed. Williams & Wilkins, Philadelphia, In Press, 2003.

Journal Publications:
Dashe JF, and Boyer PJ. Case Records of the Massachusetts General Hospital (39-1998): A 13-year old girl with a relapsing-remitting neurological disorder (MELAS). N. Engl J Med 339:1914-1923, 1998.

Kelly PJ, Toker DE, Boyer PJ, McDonald CT, and Niles J. Granulomatous compressive thoracic myelopathy as the initial manifestation of Wegener's granulomatosis. Neurology 51: 1769-1770, 1998.

Bird TD, Nochlin D, Poorkaj P, Cherrier M, Kaye J, Payami H, Peskind E, Lampe TH, Nemens E, Boyer PJ, Schellenberg GD. A clinical pathological comparison of three families with fronto-temporal dementia and identical mutations in the tau gene (P301L). Brain 122:741-756, 1999.

Rutkowski JL, Tuite GF, Lincoln P, Boyer PJ, Tennekoon GI, and Kunkel S. Role of Schwann cell-secreted cytokines in wallerian degeneration. Journal of Neuroimmunology 101:47-60, 1999.

Newell KL, Boyer PJ, Gomez-Tortoise E, Hobbs W, Hendley-Whyte ET, Richardson EP, Vonsattel JP, Hymen BT. Alpha synuclein immunoreactive neuronal cytoplasmic inclusions and axonal swellings in neuroaxonal dystrophy. Journal of Neuropathology and Experimental Neurology 58:123-1268, 1999.

Quinones-Hinojosa A, Friedlander RM, Boyer PJ, and Chiocca EA. Solitary sciatic nerve lymphoma followed by neurolymphomatosis: Case report and literature review. Journal of Neurosurgery 92:165-169, 2000.

Rutkowski JL, Wu K, Gutmann DH, Boyer PJ, and Legius E. Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1. Human Molecular Genetics 12:1059-1066, 2000.

Connor JR, Menzies S, Burdo JR, Boyer PJ. Neurobiology of iron. Journal of Pediatric Neurology 25:1180129, 2001.

Connor JR, Milward EA, Moalem S, Sampietro M, Boyer PJ, Percy ME, Vergani A, Chorney M. Is hemochromatosis a risk factor for Alzheimer disease? Journal of Alzheimer Disease 3: 471-477, 2001.

Thompson, KJ, Fried MG, Ye Z, Boyer PJ, Connor, JR. Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei. Journal of Cell Science 115: 2165-2177, 2002.

Scott KR, Simmons Z, Boyer PJ. Hypothyroid myopathy with a strikingly elevated serum creatine kinase level. Muscle and Nerve 26: 141-144, 2002.

Johnson MD, Powell SZ, Boyer PJ, Weil RJ, Moots P. Dural Lesions Mimicking Meningiomas. Human Pathology 33:1211-1226, 2002.

Erin N, Lehman RAW, Boyer PJ, Burkhart KK, Billingsley ML. In vitro hypoxia and excitotoxicity induce calcineurin-BCL-2 interactions in human brain. Neuroscience 117:557-565, 2003.

Simmons Z, Peterlin L, Boyer PJ, Towfighi J. The diagnostic yield in the evaluation of patients with modestly elevated serum creatine kinase levels. Muscle and Nerve 27: 242-244, 2003.

Henricks W, Boyer PJ, Harrison JH, Tuthill JM, Healy JC. Informatics training in pathology residency programs: Proposed learning objectives and skill sets for the new millennium. Archives Pathology and Laboratory Medicine. Archives of Pathology and Laboratory Medicine 127:1009-1018, 2003.

Takahashi K, Merchant SN, Miyazawa T, Yamaguchi T, Tsuju K, McKenna MJ, Kuroishikaawa Y, Kouda H, Okamura H, Iino Y, Sawada M, Someya T, Hashimoto R, Tamagawa Y, Takiyama Y, Nakano I, Saito K, Murakami Y, Boyer P, Nadol JB, Kitamura K. Quantitative analysis of mitochondrial DNA mutations in the inner ear of patients with MELAS and its temporal bone histopathology. The Laryngoscope 113:1362-1368, 2003.

Connor JR, Boyer PJ, Allen R, Earley C, Ondo W, Dellinger B, Menzies S, Allen R. Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome. Neurology 61: 304-309, 2003.

Erin N, Boyer PJ, Clawson G, Bonneau RH, Welch DR. Capsaicin-sensitive sensory neurons protect against metastasis. Anticancer Research 24. In Press 2004.

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Last updated: May 29, 2007