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Education and Qualifications:
Undergraduate:
BS Zoology (summa cum laude)
Arizona State University, Tempe, Arizona
1971-1975
Medical School
University of Arizona College of Medicine
Tucson, Arizona
1975-1978
Postdoctoral Training:
Intern in Pathology
The Johns Hopkins Hospital
Baltimore, Maryland
1978-1979
Assistant Resident in Pathology,
The Johns Hopkins Hospital
1979-1981
Chief Resident in Pathology
The Johns Hopkins Hospital
1981-1982
Fellow in Neuropathology,
The Johns Hopkins University School of Medicine
Baltimore, Maryland
1981-1983
Specialty Board Certification:
The American Board of Pathology:
Anatomic Pathology and Neuropathology
Licensures:
Diplomate, National Board of Medical Examiners
State of Texas #G6244
Professional Society Memberships:
U.S. and Canadian Academy of Pathology
American Association of Neuropathologists
American Society for Investigative Pathology
(Federation of American Societies for Experimental
Biology)
The Histochemical Society
Society for Neuroscience
Research Interests:
Cellular and molecular neuropathology of neurodegenerative disease, especially Alzheimer disease and related dementing disorders.
Specific topics currently under investigation include:
1) Assessment of the role of neocortical synapse loss in
production of clinical cognitive impairment
2) The effects of genetic risk factors for Alzheimer disease on
synapse integrity.
Selected Recent Publications and Presentations:
Brown, DF, et al. Neuopathologic evidence that the Lewy body variant of Alzheimer disease represents coexistence of
Alzheimer disease and idiopathic Parkinson disease. J Neuropathol Exp Neurol. 57:39-46, 1998.
Bonte, FJ, et al. Brain blood flow in the dementias: SPECT with histopathologic correlation
in 54 patients. Radiology 202:793-797, 1997.
White, CL III., et al. Production and characterization of a recombinant synaptophysin
fragment suitable for use as a standard in immunoassays. J Neuropathol Exp Neurol 56:608, 1997.
Dababo, MA, et al. Relationship between apolipoprotein E genotype and neocortical synapse
density in Alzheimer disease. J Neuropathol Exp Neurol 55:643, 1996.
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