Publications

  1. O’Donnell KA, An W, Schrum CT, Davis ES, Boeke JD. Controlled insertional mutagenesis using a LINE-1 (ORFeus) gene trap mouse model (submitted).
  2. O’Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson M, O’Malley BW, Largaespada DA, Boeke JD (2012). A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. Proc. Natl. Acad. Sci. May 22; 109(21): EE1377-86.
  3. An W, Dai L, Niewiadomska AM, Yetil A, O’Donnell KA, Han JS, Boeke JD (2011). Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs. Mobile DNA, 2(1): 2.
  4. O’Donnell KA, Burns KH (2010). Mobilizing diversity: transposable element insertions in genetic variation and disease. Mobile DNA, 1(1): 21.
  5. Kota J, Chivukula R, O’Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, and Mendell JT (2009). Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137 (6): 1005-1017.
  6. An W, Davis ES, Thompson TL, O’Donnell KA, Lee CY, Boeke JD (2009). Plug and play modular strategies for synthetic retrotransposons. Methods, 49 (3): 227-35.
  7. O’Donnell KA, Burns KH, Boeke JD (2008). A descent into the nuage: the maelstrom of transposon control. Developmental Cell 15 (2): 179-81.
  8. Ben-Aroya S, Coombes C, Kwok T, O’Donnell KA, Boeke JD, Hieter P (2008). Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Molecular Cell 30 (2): 248-258.
  9. O’Donnell KA and Boeke JD (2008). Domesticated DNA transposon proteins mediate retrotransposon control. Cell Research 18 (3): 331-333.
  10. O’Donnell KA, Boeke JD. (2007). Mighty Piwis defend the genome against genome intruders. Cell 129(1): 37-44.
  11. Dang CV, O’Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F. The c-Myc target gene network. Semin. Cancer Biol. (2006) Aug; 16 (4): 253-64.
  12. O’Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, Dang, CV. Activation of Transferrin Receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol. (2006) Mar; 26 (6): 2372-86.
  13. O’Donnell KA, Wentzel E, Zeller KI, Dang, CV, Mendell, JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 435(7043): 839-43.
  14. Dang CV, O’Donnell KA, Juopperi T. The great MYC escape in tumorigenesis. Cancer Cell. 2005 Sep;8(3): 177-178.
  15. Li F, Wonsey DR, O’Donnell KA, Kim JW, Yustein J, Lee LA, Dang CV. Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol. (2005) Jul; 25 (14): 6225-6234.
  16. Kim JW, Zeller KI, Wang Y, Jegga AG, Aronow BJ, O’Donnell KA, Dang CV. Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol. (2004) Jul; 24(13): 5923-36.
  17. Zeller KI, Jegga AG, Aronow BJ, O’Donnell KA, Dang CV. An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol. (2003); 4(10): R69. Epub 2003 Sep 11.
  18. Frischmeyer PA, van Hoof A, O’Donnell KA, Guerrerio AL, Parker R, Dietz HC. An mRNA surveillance mechanism that eliminates transcripts lacking termination codons, Science (2002); Mar 22, 295 (5563): 2258-61.

Invited Book Chapters

  1. O’Donnell KA and Mendell JT (2007). “Dysregulation of microRNAs in human malignancy.” In microRNAs: From Basic Science to Disease Biology, Cambridge University Press.
  2. Boeke JD, An W, Dai L, Davis ES, Han JS, O’Donnell KA, Scheifele LZ, Wheelan SJ (2008). Retrotransposons – Natural and Synthetic. Retrotransposition, Diversity and the Brain, FH Gage and Y Christen, Eds., Springer Verlag, Berlin, pp. 21-33.