Orth Lab


Molecular conversation with Amoeba and Bacteria

Post-translational modifications are key steps in the regulation of eukaryotic cell signaling. The modification of a protein can enhance or change the role of the protein. For instance, when a protein is phosphorylated, it might become an active enzyme, be targeted to a subcellular compartment or be efficiently degraded. In addition, the modified protein could act as a scaffold to cluster proteins and form signaling networks.