Symposium and Training II:
Advanced Clinical MRI/MRS and ¹³C MR Spectroscopy

Thursday, March 10, 1994

Presented by:
The Mary Nell and Ralph B. Rogers
Magnetic Resonance Center
and
The National Center for Research Resources

Program Objective | Guest Speakers | UT Southwestern Speakers | Program Schedule

Program Objective

This Symposium was designed to explore the prospects for clinical ¹³C and especially ¹H clinical spectroscopy, and to present research applications of ¹³C NMR.  The morning session was devoted to advanced clinical spectroscopy and emphasized ¹H chemical shift imaging of brain tumors and other regional diseases of the brain, ¹³C NMR spectroscopy of the human brain, and ³¹P NMR spectroscopy of skeletal muscle in the context of the evaluation of patients with weakness.  The afternoon session reviewed ¹³C NMR isotopomer analysis, and the application of ¹³C NMR in both animal and human studies.

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Guest Speakers

Jeffry R. Alger, Ph.D., Chief of MR Spectroscopy Section, Neuroimaging Branch, National Institutes of Health, Bethesda, MD

Steven Harms, M.D., Director of Magnetic Resonance, Baylor University Medical Center, Dallas, Texas

Heinrich Taegtmeyer, M.D., D.Phil Professor of Internal Medicine, University of Texas Health Science Center, Houston, Texas

Robert G. Weiss, M.D., Associate Professor of Internal Medicine, Johns Hopkins University, Baltimore, MD

Douglas Rothman, Ph.D., Assistant Professor of Internal Medicine, Yale University, New Haven, CT

Joseph J.H. Ackerman, Ph.D., Professor and Chairman, Department of Chemistry, Washington University, St. Louis, MO

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UT Southwestern Speakers

Ronald Haller, M.D., Associate Professor of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas

Craig R. Malloy, M.D., Associate Professor of Radiology and Internal Medicine, and Director of the Southwestern Biomedical Magnetic Resonance Facility at the Mary Nell and Ralph B. Rogers Magnetic Resonance Center, University of Texas Southwestern Medical Center, Dallas, Texas

F. Mark Jeffrey, D. Phil., Assistant Professor of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas

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Program Schedule

8:00 a.m. On Site Registration

8:30 a.m. Correlative FDG-PET and 1H MRSI Studies of Human Brain Tumors Jeffry R. Alger, Ph.D.

9:30 a.m. Breast MRI:  A New Way to Image the Breast Steven Harms, M.D.

10:15 a.m. Break

10:30 a.m. A Review of Clinical NMR Spectroscopy at 1.5 T Peter Luyten, Ph.D.

11:15 a.m. 31P NMR Spectroscopy of Metabolic Myopathies Ronald Haller, M.D.

12:00 a.m. Lunch

1:00 p.m. Control of Cardiac Function by Substrate Flux and Anaplerosis Heinrich Taegtmeyer, M.D., D.Phil.

1:30 p.m. Insights into the Pathophysiology of Myocardial Ischemia and Reperfusion with 13C Robert G. Weiss, M.D.

2:15 p.m. 13C MR Studies of Human Muscle, Liver and Brain Metabolism Douglas Rothman, Ph.D.

3:00 p.m. Break

3:30 p.m. Introduction to 13C NMR Isotopomer Analysis Craig R. Malloy, M.D.

4:00 p.m. 13C MR Monitoring of Evolving and Steady State Metabolism Joseph J.H. Ackerman, Ph.D.

4:30 p.m. Computer Models of the Citric Acid Cycle F. Mark Jeffrey, D. Phil.

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