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Thursday, May 10, 2001
Presented by:
The Mary Nell and Ralph B. Rogers
Magnetic Resonance Center
and
The National Center for Research Resources
Program Objective | Guest Speakers | UT Southwestern Speakers | Program Schedule | Corporate Sponsors
Program Objective
This program is aimed at faculty, fellows and students with an
interest in measuring fluxes in complex metabolic networks.
In the morning session, physicians and biochemists from UT
Southwestern Medical Center will provide an introduction to
2H and 13C NMR as well
as other tracer methods for analysis of metabolic problems.
Examples from biological systems ranging from cell culture to
patients will be presented. The afternoon session will
involve guest faculty and will be devoted to current concepts in
regulation of hepatic gluconeogenesis and hepatic glucose output.
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Guest Speakers
Alan D. Cherrington, Ph.D., Professor and Chairman, Molecular
Physiology and Biophysics, Vanderbilt University Medical Center,
Nashville, Tennessee.
Bernard R. Landau, M.D., Ph.D Professor of Medicine, Biochemistry
and Nutrition, Case Western Reserve University, Cleveland, Ohio.
Mark A. Magnuson, Ph.D., Assistant Vice-Chancellor for Research,
Professor of Molecular Physiology, Biophysics and Medicine,
Vanderbilt University Medical Center, Nashville, Tennessee.
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UT Southwestern Speakers
Abhimanyu Garg, M.D., Professor of Medicine, Chief, Divison of
Nutrition and Metabolic Diseases.
Craig R. Malloy, M.D., Professor of Radiology and Internal Medicine
and Director of the Southwestern Biomedical Magnetic Resonance
Facility.
Christopher B. Newgard, Ph.D., Professor of Biochemistry and
Internal Medicine and Center for Diabetes Research.
A. Dean Sherry, Ph.D., Professor of Radiology, UT Southwestern
Medical Center at Dallas and Professor of Chemistry, The University
of Texas at Dallas.
Kosaku Uyeda, Ph.D., Professor of Biochemistry.
Brian C. Weis, M.D., Ph.D Senior Research Associate, Department
of Radiology
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Program Schedule
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8:00 a.m. |
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On-Site Registration - North Campus
Continental Breakfast |
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ISOTOPE ANALYSIS OF COMPLEX METABOLIC NETWORKS
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8:30 a.m. |
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2H and 13C NMR: Principles and Potential Clinical Applications
Craig Malloy, M.D. |
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9:15 a.m. |
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The Clinical Spectrum of Insulin Resistance: From Lipodystrophy to Obesity
Abhimanyu Garg, M.D. |
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10:00 a.m. |
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Break
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10:30 a.m. |
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Analysis of Intermediary Metabolism in Patients with Liver Disease
Brian C. Weis, M.D., Ph.D. |
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11:15 a.m. |
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Metabolic Regulatory Mechanisms Revealed by Genetic Engineering and Metabolic Profiling
Christopher B. Newgard, Ph.D. |
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12:00 a.m. |
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Catered Lunch
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HEPATIC GLUCONEOGENESIS
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1:00 p.m. |
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Insulin, Glucagon and Gluconeogenesis in Vivo
Alan D. Cherrington, Ph.D. |
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2:00 p.m. |
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A Glucose-Responsive Transcription Factor that Regulates Carbohydrate Metabolism in the Liver
Kosaku Uyeda, Ph.D. |
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3:00 p.m. |
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Discussion & Break
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3:15 p.m. |
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Integration of Hepatic Energetics and Gluconeogenesis: Insights from Murine Models
Mark A. Magnuson, Ph.D. |
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4:15 p.m. |
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Gluconeogenesis and Glycogen Cycling
Bernard Landau, M.D., Ph.D. |
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Evening Session - South Campus
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5:30 p.m. |
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Reception - A.W. Harris Faculty Club
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Corporate Sponsors
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