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Thursday, April 10, 2003
Presented by:
The Mary Nell and Ralph B. Rogers
Magnetic Resonance Center
and
The National Center for Research Resources
Program Objective | Guest Speakers | UT Southwestern Speakers | Program Schedule
Program Objective
The goal of the NIH-funded Research Resource at UT Southwestern is
to develop novel NMR technologies for measuring and
understanding intermediary metabolism in vivo. One
major emphasis is to use 2H and
13C as metabolic tracers and modern NMR
methodologies to unravel the complexities of multi-organ
metabolism in animals and humans and this has been the subject of
our annual Spring symposium each of the past ten years. A
second component of the RR is to develop novel imaging agents that
respond to metabolism in vivo. Given the
widespread interest in molecular imaging tools for in
vivo detection of biological events, we decided that a
symposium limited to novel Metabolic Imaging agents would be
timely and educational.
This year's program is aimed at basic researchers and clinical
investigators with interest in imaging agents that can report on
metabolism. Although the emphasis this year will be on MR
and PET imaging agents, many of the principles are the same for
other diagnostic modalities. The morning session will
review the principles governing Gd3+-based MRI agents,
introduce the concept of paramagnetic CEST agents and
discuss potential applications, and end with talks from two
established leaders in development of responsive MR agents.
The afternoon session will focus on current and future agents
for positron emission tomography (PET) in animals and humans.
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Guest Speakers
John W. Babich, Ph.D., President, Chief Scientific Officer and
Director, Biostream, Inc Boston, Massachusetts.
Robert E. Lenkinski, Ph.D., Professor of Radiology, Harvard Medical
School, Boston, Massachusetts.
Thomas J. Meade, Ph.D., Professor, Chemistry, Biochemistry,
Molecular Biology, and Cell Biology, Neurobiology and
Physiology, Ohio State University, Evanston, Illinois.
Eva M. Sevick-Muraca, Ph.D., Professor of Chemical Engineering,
Director, Photon Migration Laboratory, Texas A&M University,
College Station, Texas.
Robert Weisskoff, Ph.D., Vice President of Business Development and
Head of Imaging, EPIX Medical, Boston, Massachusetts.
Michael J. Welch, Ph.D., Professor of Radiology, Washington
University, St. Louis, Missouri.
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UT Southwestern Speakers
Craig R. Malloy, M.D., Professor of Radiology and Internal
Medicine, UT Southwestern Medical Center.
Dana Mathews, M.D., Ph.D Associate Professor of Radiology, UT
Southwestern Medical Center.
Matthew E. Merritt, Ph.D., Senior Research Scientist, Department of
Radiology, UT Southwestern Medical Center.
Dean Sherry, Ph.D., Professor of Radiology, UT Southwestern Medical
Center and Professor of Chemistry, The University of Texas at
Dallas.
Shanrong Zang, Ph.D., Research Scientist, Department of Radiology,
UT Southwestern Medical Center.
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Program Schedule
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8:00 a.m. |
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On-Site Registration - North Campus
Continental Breakfast |
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8:45 a.m. |
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Overview of Responsive MRI Agents
Dean Sherry, Ph.D. |
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9:30 a.m. |
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Experimental Aspects of PARACEST Agents
Shanrong Zhang, Ph.D. |
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9:55 a.m. |
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Theoretical Aspects of PARACEST Agents
Matthew E. Merritt, Ph.D. |
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10:15 a.m. |
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Break
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10:45 a.m. |
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Agents for Metabolic Imaging of Fibrin
Robert Weisskoff, Ph.D., M.B.A. |
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11:35 a.m. |
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Seeing is Believing
Thomas J. Meade, Ph.D. |
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12:15 a.m. |
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Catered Lunch
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1:30 p.m. |
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Overview of Clinical PET
Dana Mathews, M.D., Ph.D. |
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2:15 p.m. |
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Metabolic Measurements using PET, From Mouse to Man
Michael J. Welch, Ph.D. |
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3:00 p.m. |
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Discussion / Break
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3:30 p.m. |
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Fatty Acid Analogs for PET Imaging
John W. Babich, Ph.D. |
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4:15 p.m. |
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Fluorescence-enhanced Diagnostic Imaging of Cancer
Eva Sevick-Muraca, Ph.D. |
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5:00 p.m. |
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Emergence of Metabolic Imaging as a Research Priority
Robert E. Lenkinski, Ph.D. |
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5:30 p.m. |
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Wine and Cheese Reception at the A. W. Harris Faculty Club
South Campus |
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