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Symposium and Training XIII:
Prospects of Biochemical Imaging:
The Brain & Beyond

Thursday, April 14, 2005

Presented by:
The Mary Nell and Ralph B. Rogers
Magnetic Resonance Center

and
The National Center for Research Resources

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National Center for Research Resources logo



Program Objective | Guest Speakers | UT Southwestern Speakers | Program Schedule | Acknowledgments

 

Program Objective

The goal of the NIH-funded Research Resource at UT Southwestern is to develop novel Nuclear Magnetic Resonance (NMR) technologies for measuring and understanding intermediary metabolism in vivo.  One major emphasis is to use 2H and 13C as metabolic tracers and modern NMR methodologies to unravel the complexities of multi-organ metabolism in animals and humans.  A second component of the Research Resource is to develop novel imaging agents that respond to metabolism in vivo.

There is widespread interest in brain activation as well as excitement about the potential for both spectroscopy and molecular imaging tools for in vivo detection of activation.  We decided that a symposium emphasizing the current methods for detecting brain activation by MR would be timely and educational.  Therefore, outstanding speakers in brain metabolism and physiology will discuss their work and the core research interests of this group will be discussed in the context of application to brain studies.

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Guest Speakers

Pierre-Gilles Henry, Ph.D., Research Associate, Center for Magnetic Resonance Research, University of Minnesota

Ralph E. Hurd, Ph.D., Chief Scientist and Director, Biochemical Imaging Laboratory, GE Healthcare Technologies

Fahmeed Hyder, Ph.D., Associate Professor of Diagnostic Radiology and Biomedical Engineering, Yale University

Allen Song, Ph.D., Associate Professor of Radiology, Center for Brain Imaging & Analysis, Duke University

Keith Thulborn, M.D., Ph.D. Professor of Radiology and Director of Center for MR Research, University of Illinois at Chicago

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UT Southwestern Speakers

Craig Malloy, M.D., Professor of Radiology and Internal Medicine and Staff Physician, VA North Texas Health Care System

Shawn Burgess, Ph.D., Assistant Professor of Radiology

Dean Sherry Ph.D., Professor of Radiology & Professor of Chemistry, University of Texas at Dallas

Carol Tamminga, M.D., Professor of Psychiatry

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Program Schedule

8:00 a.m.
On-Site Registration - North Campus
Continental Breakfast
8:30 a.m.
Metabolic Pathways by Stable Isotopes and NMR
Shawn Burgess, Ph.D.
9:15 a.m.
Isotopomer Analysis and Biochemical Fluxes
Craig R. Malloy, M.D.
10:00 a.m.
Break
10:15 a.m.
Measuring Brain Energy Metabolism and Glutamatergic Neurotransmission in the Brain using 13C NMR
Pierre-Gilles Henry, Ph.D.
11:00 a.m.
Principles and Prospects of Hyperpolarized 13C
Ralph E. Hurd, Ph.D.
12:00 a.m.
Catered Lunch
1:00 p.m.
Using In Vivo Imaging to understand Diseases of the Brain
Carol Tamminga, M.D.
1:45 p.m.
Magnetic Resonance Imaging of Minute Electrical Activities
Allen Song, Ph.D.
2:30 p.m.
Cellular Physiology of Brain Activation
Fahmeed Hyder, Ph.D.
3:15 p.m.
Discussion / Break
3:45 p.m.
Human Brain Metabolic Studies at High Fields
Keith Thulborn, M.D., Ph.D.
4:30 p.m.
Metabolic Imaging of Tissues using Responsive Magnetic Resonance Imaging Agents
A. Dean Sherry, Ph.D.
5:30 p.m.
Wine and Cheese Reception

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Acknowledgments

Original image of cover figure courtesy of Carol Tamminga, M.D.

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