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WEDNESDAY, MAY 20, 2009 & Thursday, MAY 21, 2009
Presented by:
The Advanced Imaging Research Center
and
NIH National Center for Research Resources
Program Objective | Guest Speakers | UT Southwestern Speakers | Program Schedule | Registration | Program Site | Acknowledgments
Program Objective
The goal of the NIH-funded Research Resource at UT Southwestern is
to develop novel Nuclear Magnetic Resonance (NMR) technologies for
measuring and understanding intermediary metabolism in
vivo. One major emphasis is to use
2H and 13C as metabolic
tracers and modern NMR methodologies to unravel the complexities of
multi-organ metabolism in animals and humans. A second
component of the Research Resource is to develop novel imaging
agents that respond to metabolism in vivo. There is
widespread interest in brain activation as well as excitement about
the potential for both spectroscopy and molecular imaging tools for
in vivo detection of activation. We decided that a
symposium emphasizing the current methods for detecting brain
activation by MR would be timely and educational. Therefore,
outstanding speakers in brain metabolism and physiology will
discuss their work and the core research interests of this group
will be discussed in the context of application to brain studies.
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Guest Speakers
Kevin Brindle, Ph.D., University of Cambridge
Arnaud Comment, Ph.D., Ecole Polytechnique Federale de Lausanne
Charles Cunningham, Ph.D., University of Toronto
Klaes Golman, Ph.D., Imagnia AB
Aaron Grant, Ph.D., Harvard University
John Kurhanewicz, Ph.D., University OF California
Robert Shulman, Ph.D., Yale University
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UT Southwestern Speakers
Shawn Burgess, Ph.D., Advanced Imaging Research Center, UTSW
F. Mark Jeffrey, Ph.D., Advanced Imaging Research Center,
UTSW
Craig Malloy, M.D., Advanced Imaging Research Center, UTSW, VA
Medical Center at Dallas
Matthew Merritt, Ph.D., Advanced Imaging Research Center, UTSW
Juan Pascual, M.D., Ph.D Neurology & Pediatric Neurology,
UTSW
A. Dean Sherry Ph.D., Advanced Imaging Research Center, UTSW,
University of Texas at Dallas
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Program Schedule
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TEACHING SESSION
Wednesday, May 20, 2009
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12:00 a.m. |
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On-Site Registration - North Campus
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1:00 p.m. |
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How NMR Illuminates Physiology and Medicine
Robert Shulman, Ph.D. |
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2:00 p.m. |
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Carbon Tracers and Enzyme Kinetics
A. Dean Sherry, Ph.D. |
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2:30 p.m. |
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Subtrate Oxidation in Heart and Skeletal Muscle
Craig Malloy, M.D. |
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3:00 p.m. |
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Discussion and Break
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3:30 p.m. |
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Glucose Production and Complex Networks in Pancreas and Liver
Shawn Burgess, Ph.D. |
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4:00 p.m. |
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Neurotransmitter Synthesis in the Mouse Brain
Juan Pascual, Ph.D. |
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4:15 p.m. |
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Data Analysis and Computer Models: Examples
F. Mark Jeffey, D. Phil. |
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4:30 p.m. |
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Sample Spectra and Discussion. Problem Sets
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HYPERPOLARIZATION IN BIOLOGY
Thursday, May 21, 2009
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8:00 p.m. |
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On-Site Registration - North Campus
Continental Breakfast
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9:00 p.m. |
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Introduction to Dynamic Nuclear Polarization
Matthew Merritt, Ph.D. |
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9:45 p.m. |
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The Journey of DNP-Enhanced Nuclear Spins: From the Polarizer to the Rat Brain
Arnaud Comment, Ph.D. |
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10:30 p.m. |
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Discussion and Break
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11:00 p.m. |
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Hyperpolarization and Long-Lived States: Circumventing T1 Barriers
Aaron Grant, Ph.D. |
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11:45 p.m. |
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Discussion
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12:00 p.m. |
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Catered Lunch
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1:00 p.m. |
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13C Hyperpolarization: History, Results and Applications!
Klaes Golman, Ph.D. |
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2:00 p.m. |
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How to Image Hyperpolarized 13C
Charles Cunningham, Ph.D. |
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2:45 p.m. |
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Discussion and Break
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3:00 p.m. |
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Imaging Tumour Responses to Treatment with Hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging
Kevin Brindle, Ph.D. |
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3:45 p.m. |
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Early Clinical Perspectives on Hyperpolarized 13C
John Kurhanewicz, Ph.D. |
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4:30 p.m. |
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Discussion
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4:45 p.m. |
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Reception
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Registration
Registration is complimentary, but in order to guarantee your lunch
and course materials, we do require a completed registration form
prior to May 15, 2009. To register, please print and fill
out the form from the brochure, and
mail directly or fax to (214) 648-4804.
For more information, please contact Continuing Medical Education,
(214) 648-3138.
UT Southwestern / Continuing Medical Education
Symposium and
Training XVII Registration
5323 Harry Hines Boulevard
Dallas, Texas 75390-9059
Phone (214) 648-3138,
1-800-688-8678
Fax (214) 648-4804
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Program Site
UT Southwestern Medical Center, North Campus, T. Boone
Pickens Biomedical Building Auditorium, 6001 Forest Park Road,
Dallas, Texas 75235. There is a shuttle that runs between
the North Campus and South Campus between 7 a.m. and 7
p.m. Visitor parking is provided at the main entrance of
both the NG and the ND tower at 6001 Forest Park.
Detailed maps of UT Southwestern campuses and surrounding areas may
be viewed here.
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Acknowledgments
Original image courtesy Dr. Kevin Brindle and Macmillan
Publishers Limited. Redrawn from Nature. 2008;
453:940-3.
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