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Elliott M. Ross |
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Finly Philip I am using engineered fluorescent phospholipase C (PLC) biosensors to study putative conformational changes in PLC-β1 upon activation and to determine the dynamics of G protein regulation of PLC. I am also interested in using these biosensors to study the mechanisms that regulate activation and deactivation of PLC-β1 and Gαq both in cells and in vitro, and how these mechanisms relate to regulation of PLC-β's and Gβγ. |
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Seungwoo Chang Seungwoo is studying conformational isomerization of M1 muscarinic cholinergic receptors and its regulation by agonists and Gq using fluorescent conformational reporter constructs, which he has engineered. |
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Ganesh Kadamur Ganesh is interested in understanding the mechanisms of inhibition of GAP activity by Gβγ using mutational analysis and related biophysical approaches. Life in lab apart, he is interested in the outdoors and is an avid photographer, and is known for his ability to keep talking for very long. |
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Jimmy Woodson |
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Anna Dugas |
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Elisha White Technician Elisha.White@utsouthwestern.edu |






