The Tu Lab is interested in the study of metabolic cycles and how biological processes (e.g., cell growth and division, transcription, translation, mitochondrial homeostasis, autophagy) are coupled to metabolism and the metabolic state of a cell.

Bow to the metabolites.

Three metabolic phases in the life of a yeast cell.

Many biological cycles might fundamentally be metabolic cycles.

Check out how a PUF RNA-binding protein switches the fate of its target mRNA transcripts. There is a low complexity region involved and at the time few believed this part of the protein could be important.

See how the metabolic state influences a conserved RNA modification in the regulation of protein translation.

A surprising link between metabolism and epigenetics.

Could this be the most fundamental function of TORC1 and explain the role of its negative regulation? And a reason for the Warburg effect?

Eight molecules that power cell metabolism.

A mechanism by which histone demethylation is regulated.

What are the normal functions of ataxin-2, a protein linked to neurodegenerative disease?

And a neat redox regulatory mechanism.

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