Wakeland Publications

Selected publications (from > 170)

1. Morel, L., U.H. Rudofsky, J.H. Longmate, and E.K. Wakeland: Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1:219-229, 1994. PMID: 7889410

2. Morel, L., Tian, X-H., Croker, B.P. and Wakeland, E.K. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity, 11: 131-139, 1999. PMID: 10485648

3. Morel, L., Croker, B.P., Blenman, K. R., Mohan, C., Huang, G., Gilkeson, G., and Wakeland, E.K. Genetic reconstitution of systemic lupus erythematosus immunopathology with poly-congenic murine strains, Proc. Natl. Acad. Sci., 6670-6675, 2000. PMCID: PMC18697

4. Morel, L., Blenman, K.R., Croker, B.P., Wakeland, E.K., The major murine SLE-Susceptibility locus, Sle1, is a cluster of functionally related genes. Proc. Natl. Acad. Sci., 98:1787-1792, 2001. PMCID: PMC29335

5. Wandstrat, A, Wakeland, E.K., The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nature Immunology, 9:802-809, 2001. PMID: 11526390

6. Boackle, S.A., Holers, V. M., Chen, X., Szakonyi, G., Karp, D.R., Wakeland, E.K., Morel, L., Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional Protein, Immunity, 15:775-785, 2001. PMID: 11728339

7. Wandstrat,,A.E., Nguyen,C., Limaye,N., Chan,A.Y., Subramanian,S., Tian,X.-H.,Yim,Y.-S., Pertsemlidis,A., Garner,H.R. Jr., Morel,L., and Wakeland,E.K., Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity, 21:769-780, 2004. PMID: 15589166

8. Subramanian, S., Tus, K., Li, Q.-Z., Wang, A., Tain, X.-H., Zhou, J., Liang, C., Barov, G., McDaniel, L.D., Zhou, X.J., Schultz, R.A., and Wakeland, E.K. From the cover: A Tlr7 translocation accelerates systemic autoimmunity in murine lupus, Proc.Natl.Acad.Sci, 103:9970-9975, 2006. PMCID: PMC1502563

9. Kumar, K.R., Li, L., Bhaskarabhatla, M., Yan, M. Schatzle, J.D., Wakeland, E.K., and Mohan, C. Regulation of B cell tolerance by the lupus susceptibility gene Ly108, Science, 312:1665-1669, 2006. PMID: 16778059

10. Sawalha, A.H., Kaufman, K.M., Kelly, J.A., Adler, T., Aberle, J., Kipatrick, J., Wakeland, E.K., Li, Q.Z., Wandstrat, A.E., Karp, D.S., James, J.A., Merill, J.T., Lipsky, P., and Harley, J.B. Genetic Association of IL-21 polymorphisms with systemic lupus erythematosus, Ann. Rheum.Dis., 67:458-461, 2008. PMID: 17720724

11. Limaye, N., Belobrajdic, K., Wandstrat, A.E., Bonhomme,F., Edwards, S.V., and Wakeland, E.K. Prevalence and evolutionary origins of autoimmune susceptibility alleles in natural mouse populations. Genes and Immunity, 9:61-68, 2008. PMID: 18094711

12. Harley, J. B. Alarcon-Riquelme, M. E., Criswell, L. A., Jacob, C. O., Kimberly, R. P., Moser, K. L., Tsao, B. P., Vyse, T.J., Langefeld, C. D., Nath, S. K., Guthridge, J. M., Cobb, B. L., Mirel, D. B., Marion, M. C., Williams, A. H, Divers, J., Wang, W., Frank, S. G., Namjou, B., Gabriel, S. B., Lee, A. T., Gregersen, P. K., Behrens, T. W., Taylor, K. E., Fernando, M., Zidovetzki, R., Gaffney, P. M., Edberg, J. C., Rioux, J. D., Ojwang, J. O., James, J. A., Merrill, J. T., Gilkeson, G. S., Seldin, M. F., Yin, H., Baechler, E. C., Li, Q. Z., Wakeland, E. K., Bruner, G. R., Kaufman, K. M. Kelly, J. A. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542, and other loci, Nature Genetics, 40:204-210, 2008. PMID: 18204446

13. Nath, S. K., Han, S., Kim-Howard, X., Kelly, J. A., Viswanathan, P., Gilkeson, G. S., Chen, W., Zhu, C., McEver, R. P., Kimberly, R. P., Alarcon-Riquelme, M. E., Vyse, T. J., Li, Q. Z., Wakeland, E. K., Merrill, J. T., James, J. A., Kaufman, K. M., Guthridge, J. M., Harley, J. B. A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nature Genetics 40: 152-154, 2008. PMID: 18204448

14. Kelly, J. A., Kelley, J. M., Kaufman, K. M., Kilpatrick, J., Bruner, G. R., Merrill, J. T., James, J. A., Frank, S. G., Reams, E., Brown, E. E., Gibson, A. W., Marion, M. C., Langefeld, C. D., Li, Q. Z., Karp, D. R., Wakeland, E. K., Petri, M., Ramsey-Goldman, R., Reveille, J. D., Vila, L. M., Alarcon, G. S., Kimberly, R. P., Harley, J. B., Edberg, J. C. Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans. Genes and Immunity, 9:187-94, 2008. PMID: 18288123

15. Liu, K.*, Li, Q.Z.*, Delgado-Vega, A., Abelson, A.K.*, Sánchez, E.*, Kelly, J.A.*, Li, L., Cheung1, S., Liu, Y., Zhou, J., Yan, M., Ye, Q., Liu, S., Xie, C., Zhou, X.J., Pons-Estel, B., Witte, T., de Ramón, E., Bae, S.C., Barizzone, N., Sebastiani, G.D., Merrill, J.T., Gregersen, P.K., Gilkeson, G.G., Kimberly, R.P., Vyse, T.J., Kim, I.L., The Italian Collaborative Group, The German Collaborative Group, The Spanish Collaborative Group, The Argentinian Collaborative Group, The SLEGEN Consortium, D'Alfonso, S., Martin, J., Harley, J.B., Criswell, L.A., Alarcón-Riquelme, M.E., Wakeland, E.K., Mohan, C. Kallikreins as disease genes in lupus and anti-glomerular antibody-induced nephritis. Journal of Clinical Investigation, 119(4):911-923, 2009. (*co-first authors). PMCID: PMC2662554.