List of Publications
Yu, Y., Chen, Y., Kim, B., Wang, H., Zhao, C., He, X., Liu, L., Wu, N., Chan, J., Wu, J., and Lu, Q.R. (2013). Olig2 pre-patterns the Chromatin Remodeler Smarca4/Brg1 to Establish Oligodendrocyte Identity and CNS Myelination. Cell 152, 248-261.
Limpert, A.S., Bai S., Narayan M., Wu, J., Yoon S.O., Carter B.D., Lu Q.R. (2013). NF-?B Forms a Complex with the Chromatin Remodeler BRG1 to Regulate Schwann Cell Differentiation. J. Neurosci 33, 2388-2397
Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, Babayan AH, Wu JI, Crabtree GR, Baldi P, Baram TZ, Lynch G, Wood MA. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat Neurosci. 2013 May;16(5):552-61.
Wu, J.I. (2012) Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancer. Acta Biochimica et Biophysica Sinica. 44, 54-69
Zhan, X., Shi, X., Zhang, Z., Chen, Y., Wu, J.I. (2011) Dual role of Brg chromatin remodeling factor in Shh signaling during neural development. Proc. Natl. Acad. Sci. USA, 108, 12758-12763. PMC315094
Zhan, X., and Wu, J. (2009) Epigenetics in embryonic and adult neurogenesis. Cell Science Review 6, 104-128
Ho L, Ronan JL, Wu J, Staahl BT, Chen L, Kuo A, Lessard J, Nesvizhskii AI, Ranish J, Crabtree GR. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci U S A., 106(13):5181-6
Wu, J. I., Lessard, J., and Crabtree, G. R. (2009) Understanding the words of chromatin remodeling. Cell, 136(2):200-6..
Stankunas, K., Hang, C.T., Tsun, Z.Y., Chen, H., Lee, N.V., Wu J.I., Shang, C., Bayle, J.H., Shou, W., Iruela-Arispe, M.L., Chang, C.P. (2008) Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev. Cell 14, 298-311.
Wu, J. I., Lessard, J., Olave, I. A., Qiu, Z. Ghosh, A., Graef, I. A., and Crabtree, G. R. (2007). Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 56, 94-108 (featured in Leading Edge Cell 131, 199; Research Focus in Trends in Cell Biology 18, 48-51; Featured article in Nature Neuroscience Gateway Oct. 2007).
Lessard, J.*, Wu, J. I.*,
Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H.,
Aebersold, R., Graef, I. A., and Crabtree, G. R. (2007). An essential
switch in subunit composition of a chromatin remodeling complex during
neural development. Neuron 55, 201-215 (cover and preview Neuron 55, 171-173).
*: Equal contribution.
Wu, J. I. and Crabtree, G. R. (2007) Cell signaling. Nuclear actin as choreographer of cell morphology and transcription. Science 316:1710-1711
Book Chapter
Artzt, K and Wu, J.I. (2010) STAR TREK: An introduction to STAR family proteins and review of QKI. Post-Transcriptional Regulation by STAR Proteins: Control of RNA Metabolism in Development and Disease Landes Bioscience, ISBN 978-1-4419-7004-6.
From Graduate School
Wu, J. I., Rajendra, R., Barsi, J.C., Durfee, L., Benito, E., Gao, G., Kuruvilla, M., Hrdlickova, R., Liss, A. S., Artzt, K. (2007) Targeted disruption of Mib2 causes exencephaly with a variable penetrance. Genesis 45, 722-727.
Wu, J. I., Centilli, M. A., Vasquez G., Young, S., Scolnick, J., Durfee L. A., Spearow, J. L., Schwantz S. D., Rennebeck G., and Artzt K. (2007). tint maps to mouse chromosome 6 and may interact with a notochordal enhancer of Brachyury. Genetics 177, 1151-1161
Barsi, J.C.*, Rajendra, R.*, Wu, J.I.*, and Artzt, K. (2005) Mind bomb 1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech. Dev. 122: 1106-1117. (cover)
*: Equal contribution.
Wu, J.I., Reed R.B., Grabowski, P. J., and Artzt, K. (2002) The function of quaking in myelination: alternative splicing regulation. Proc. Natl. Acad. Sci. USA 99: 4233-4238.
Reddy, T.R., Modem, S., Xu, W., Yeh, L., Yang, J.P., Wu, J., Artzt, K., and Wong-Staal, F. (2002) A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication . J. Biol. Chem.277: 5778-5784.
Wu, J., Zhou L., Tonissen k. , Tee R., and Artzt, K. (1999) The quakingI-5 (QKI-5) protein has a novel nuclear localization signal and shuttles between the nucleus and the cytoplasm. J. Biol. Chem. 274: 29202-29210.
Kondo, T., Furuta, T., Mitsunaga, K., Ebersole, T.A., Shichiri, M., Wu, J., Artzt, K., Yamamura, K., and Abe, K. (1999) Genomic organization and expression analysis of the mouse qkI locus. Mamm. Genome 10:662-669.
Venables, J.P., Vernet, C., Chew, S.L., Cowmeadow, R.B., Wu, J., Cooke, H.J., Artzt, K. and Eperon, I.C. (1999) T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis. Hum Mol Genet; 8: 959-969.